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Clinical Trials/NCT02626143
NCT02626143
Completed
N/A

Effect of Feeding Mode on Infant Growth and Cognitive Function

Mead Johnson Nutrition1 site in 1 country582 target enrollmentFebruary 2016

Overview

Phase
N/A
Intervention
Not specified
Conditions
Infant Nutrition
Sponsor
Mead Johnson Nutrition
Enrollment
582
Locations
1
Primary Endpoint
Head circumference
Status
Completed
Last Updated
5 years ago

Overview

Brief Summary

This study is intended to compare growth, nutritional status, and brain development in children fed an Investigational cow's milk based formula containing a nutrient-rich whey protein, a standard cow's milk based formula, or fed exclusively breast milk.

Registry
clinicaltrials.gov
Start Date
February 2016
End Date
March 2019
Last Updated
5 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Mead Johnson Nutrition
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Singleton, 0-120 days of age at study entry
  • Term infant with birth weight of 2500 to 4500 grams
  • Exclusively feed infant formula or exclusively feeding breast milk
  • Signed informed consent

Exclusion Criteria

  • History of underlying metabolic or chronic disease, congenital malformation, or immunocompromised.
  • Feeding difficulties or formula intolerance
  • Receiving complementary feedings

Outcomes

Primary Outcomes

Head circumference

Time Frame: 24 months

Auditory Event-related Potential

Time Frame: 24 months

Body length

Time Frame: 24 months

Body weight

Time Frame: 24 months

Secondary Outcomes

  • Medically confirmed adverse events(24 months)
  • Body Composition: Deuterium Dilution(12 and 24 months)
  • Language development: Rule Inference(10 months)
  • Language development: Word Discovery(10 months)
  • Dietary Intake(24 months)
  • Blood sample: Metabolic markers(24 months)
  • Blood sample: Micronutrient status(24 months)
  • Language development: Native3 Phoneme Repertory(12 months)
  • Body Composition: Air Displacement Plethysmography(6 months)
  • Bayley Scales of Infant and Toddler Development(12 months)
  • Sleep measures (Amount of time awake & asleep in a 7-day period)(24 months)
  • Language development: MacArthur Communicative Development Inventory(24 months)

Study Sites (1)

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