NCT00174317已完成4 期
Clinical Protocol For A Multicentre, Double-Blind, Randomised, Parallel Group Study To Compare The Efficacy and Tolerability Of Celecoxib Vs. Diclofenac In The Treatment Of Subjects With Osteoarthritis Of The Hip Requiring Joint Replacement Therapy
适应症
相关药物
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- Pfizer
- 入组人数
- 250
- 试验地点
- 45
- 主要终点
- Change in patient assessment of arthritis pain on walking VAS (Visual Analog Scale) as measured on a 0-100 mm scale at week 6 compared to baseline
研究概览
简要总结
To determine if celecoxib 200 mg once daily is as effective as diclofenac 50 mg three times daily in the treatment of pain symptoms associated with osteoarthritis of the hip
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double
入排标准
- 年龄范围
- 45 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Diagnosed with osteoarthritis of hip and requiring joint replacement
- •Eligible for chronic therapy with an NSAID
排除标准
- •Hip surgery anticipated within 8 calendar weeks after first visit
- •Active gastrointestinal disease or recent diagnosis of gastrointestinal ulceration (within 60 days of first visit)
结局指标
主要结局
Change in patient assessment of arthritis pain on walking VAS (Visual Analog Scale) as measured on a 0-100 mm scale at week 6 compared to baseline
次要结局
- Change in patient assessment of arthritis pain on walking VAS (Visual Analog Scale) as measured on a 0-100 mm scale at week 12 compared to baseline.
- Change in patients global assessment of arthritis between treatment groups.
研究者
研究点 (45)
Loading locations...
相似试验
已完成
4 期
Study Of Celecoxib Or Diclofenac And Omeprazole For Gastrointestinal (GI) Safety In High GI Risk Patients With ArthritisArthritis, RheumatoidOsteoarthritisNCT00141102Pfizer's Upjohn has merged with Mylan to form Viatris Inc.4,484
已完成
3 期
Safety and Efficacy of Celecoxib Versus Diclofenac in the Treatment of Ankylosing SpondylitisSpondylitis, AnkylosingNCT00648141Pfizer458
已完成
4 期
Safety And Efficacy Of Celecoxib Versus Sodium Diclofenac In The Treatment Of Acute Low Back PainLow Back PainNCT00640432Pfizer's Upjohn has merged with Mylan to form Viatris Inc.244
已完成
2 期
Study To Evaluate Efficacy And Safety Of An Additional Dose Of Celecoxib (YM177) In Patients With Post-Tooth Extraction PainPainNCT01062113Pfizer's Upjohn has merged with Mylan to form Viatris Inc.255
已完成
4 期
A Study Of Celecoxib Versus Diclofenac In Patients With Ankylosing SpondylitisAnkylosing SpondylitisNCT02528201Pfizer330