Celecoxib Versus Diclofenac In The Treatment Of Osteoarthritis Of The Hip

Phase 4

Completed

• Conditions: Osteoarthritis, Hip

• Registration Number: NCT00174317
• Lead Sponsor: Pfizer

Brief Summary

To determine if celecoxib 200 mg once daily is as effective as diclofenac 50 mg three times daily in the treatment of pain symptoms associated with osteoarthritis of the hip

Detailed Description

Not available

Study Timeline

• Study Start: 2003-08
• Study Completion: 2005-02
• Study First Submitted: 2005-09-09
• Study First Submitted QC: 2005-09-09
• Study First Posted: 2005-09-15
• Status Verified: 2005-12
• Last Update Submitted: 2006-11-30
• Last Update Posted: 2006-12-05

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 250

Inclusion Criteria

• Diagnosed with osteoarthritis of hip and requiring joint replacement
• Eligible for chronic therapy with an NSAID

Exclusion Criteria

• Hip surgery anticipated within 8 calendar weeks after first visit
• Active gastrointestinal disease or recent diagnosis of gastrointestinal ulceration (within 60 days of first visit)

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Change in patient assessment of arthritis pain on walking VAS (Visual Analog Scale) as measured on a 0-100 mm scale at week 6 compared to baseline

Secondary Outcome Measures

Name	Time	Method
Change in patient assessment of arthritis pain on walking VAS (Visual Analog Scale) as measured on a 0-100 mm scale at week 12 compared to baseline.
Change in patients global assessment of arthritis between treatment groups.

Trial Locations

Locations (1)

Pfizer Investigational Site; 🇬🇧 Wigan, United Kingdom