Effect of Recent Alcohol, Smoking and Psychotropic Drug Use on Delirium in ICU
试验速览
- 阶段
- 不适用
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- Delirium during ICU stay
研究概览
简要总结
Investigators are seeking to determine the impact of recent alcohol, smoking or psychotropic drug use prior to intensive care unit (ICU) admission on incidence of delirium and sedation requirements.
Study design: A prospective observational study, in a medical ICU of a tertiary university hospital.
Methods: For all new ICU admissions, a 1-page questionnaire including Alcohol Use Disorders Identification Test (AUDIT-C), smoking history and prior medication use was given to the patient or closest family members.
Delirium was assessed by trained ICU nurses using Intensive Care Delirium Screening Checklist and Richmond Agitation-Sedation Scale.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients who are older than 18 years of age
- •New patients admitted to medical ICU for the 1st time during their stay in hospital
排除标准
- •Had history of stroke or other primary neurologic disease
- •GCS ≤ 8 prior to ICU admission
- •Transferred from other ICU (except for emergency ICU stay which is limited to less than 36 hours)
- •Not registered within 24 hours after admission
- •Refused to participate
- •If comatous state persists
- •Delirium assessment is not possible due to newly developed neurologic disease, such as cerebral infarction
- •Medical ICU stay less than 24 hours
- •Readmission to medical ICU
结局指标
主要结局
Delirium during ICU stay
时间窗: From date of ICU admission until the date of ICU discharge, whichever came first, assessed up to 3 months
次要结局
- ICU length of stay(From date of ICU admission until the date of first documented discharge from ICU or death, whichever came first, assessed up to 3 months)
- Maximal doses of dexmedetomidine(From date of ICU admission until the date of first documented discharge from ICU or death, whichever came first, assessed up to 3 months)
- Cumulative dose of dexmedetomidine(From date of ICU admission until the date of first documented discharge from ICU or death, whichever came first, assessed up to 3 months)
- Mortality(From date of ICU admission until the date of death, assessed up to 3 months)
- Cumulative dose of midazolam(From date of ICU admission until the date of first documented discharge from ICU or death, whichever came first, assessed up to 3 months)
研究者
Jinwoo Lee
Professor
Seoul National University Hospital