Role of salivary biomarkers during fixed appliance treatment
- Conditions
- Health Condition 1: K089- Disorder of teeth and supporting structures, unspecifiedHealth Condition 2: M264- Malocclusion, unspecified
- Registration Number
- CTRI/2020/12/029660
- Lead Sponsor
- All India Institute of Medical Sciences Jodhpur
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 20
1) Patient requiring extraction of 4 premolars for correction(class II div.1 malocclusion, Bimaxillary protrusion)
2) Patient above 12 years of age
3) Need for fixed appliance therapy involving tooth extractions, good general and periodontal health
4) Good oral hygiene
5) Full permanent dentition including the
maxillary second molars
1) Pregnancy and lactation
2) Patients who would not give informed consent
3) Patients consuming alcohol or tobacco use.
4) Any systemic condition that could affect periodontal status
5) Previous history of orthodontic treatment
6) Patient with disorders of bone metabolism (e.g., osteoporosis, gastrointestinal diseases related to nutrition and mineral metabolism, endocrine diseases, immunologic disorders, and connective tissue diseases)
7) Patient already under medication for treatment of conditions like heart conditions, joint replacements, hormonal or bisphosphonate antiresorptive therapies, and chronic therapy with heparin or corticosteroids.
8) Patients with developmental anomalies like, cleft lip and palate and other craniofacial abnormalities
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method