NCT01780311
Unknown
Phase 4
Catheter Ablation Versus Antiarrhythmic Drugs for Outflow Tract Ventricular ARrhythmias
Overview
- Phase
- Phase 4
- Intervention
- antiarrhythmic drugs (Flecainide or Propafenone or Sotalol)
- Conditions
- Ventricular Tachycardia
- Sponsor
- Ospedale San Donato
- Locations
- 1
- Primary Endpoint
- SF-36 score
- Last Updated
- 13 years ago
Overview
Brief Summary
A randomized, parallel, open study comparing catheter ablation versus antiarrhythmic drugs for outflow tract ventricular arrhythmias
Investigators
Leonardo Bolognese, MD
Director
Ospedale San Donato
Eligibility Criteria
Inclusion Criteria
- •presence of ventricular ectopic beats (VEB) with left-bundle-branch block morphology or right-bundle-branch block morphology and positive concordance throughout the chest leads, inferior axis and at least one of the following:
- •\>2000 isolated VEB/24h
- •symptomatic monomorphic ventricular tachycardia
- •left ventricular disfunction supposed to be due to tachycardia-induced cardiomyopathy
Exclusion Criteria
- •known structural heart disease
- •life expectancy \< 1 year
Arms & Interventions
Antiarrhythmic drugs
Flecainide or Propafenone or Sotalol (oral, standard dosage)
Intervention: antiarrhythmic drugs (Flecainide or Propafenone or Sotalol)
ABLATION
Catheter Ablation
Intervention: Catheter Ablation
Outcomes
Primary Outcomes
SF-36 score
Time Frame: 6 months
Quality of life improvement according to SF-36 score variations
Study Sites (1)
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