MedPath

Clinical Results of Asqelio Trifocal Diffractive Intraocular Lens

Active, not recruiting
Conditions
Cataract
Registration Number
NCT05065749
Lead Sponsor
AST Products, Inc.
Brief Summary

The study aims to evaluate the clinical outcomes six months after implantation of the trifocal diffractive intraocular lens Asqelio Trifocal IOL TFLIO130C in healthy subjects submitted to non-traumatic cataract surgery.

This clinical performance will be assessed in terms of refractive error, visual performance at different distances, incidence of adverse events and complications following implantation, and patient satisfaction.

Detailed Description

Not available

Recruitment & Eligibility

Status
ACTIVE_NOT_RECRUITING
Sex
All
Target Recruitment
30
Inclusion Criteria
  • Patients submitted to cataract surgery and implanted with Asqelio Trifocal IOL TFLIO130C
  • Patients signing a consent form
  • Patients seeking spectacle-independence following surgery
  • IOL power between +5.00 and +34.00 D
  • Transparent intraocular media, except for the cataract prior to surgery, in both eyes
  • Postoperatory potential visual acuity of 20/25 or better.
Exclusion Criteria
  • Preoperatory corneal astigmatism greater than 0.75D
  • Patients not providing informed consent
  • Previous corneal surgery or trauma
  • Irregular cornea (i.e. keratoconus)
  • Choroidal hemorrhage
  • Microophthalmos
  • Severe corneal dystrophy
  • Uncontrolled or medically controlled glaucoma
  • Clinically significant macular changes
  • Severe concomitant ocular disease
  • Not age-related cataract
  • Severe optic nerve atrophy
  • Diabetic retinopathy
  • Ambyopia
  • Extremely shallow anterior chamber
  • Severe chronic uveitis
  • Pregnant or lactating
  • Rubella
  • Mature/Dense cataract sifficulting preoperative fundus assessment
  • Previous retinal detachment
  • Concurrent participation in other investigation using drugs or clinical devices
  • Expecting ocular surgery within the study period

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Adverse eventsSix months after implantation

Percentage of subjects with adverse events (Ocular and Not Ocular, Severe and Not Severe), including secondary surgical procedures

RefractionSix months after implantation

Manifest refraction both monocular and binocularly using subjective methods

Secondary Outcome Measures
NameTimeMethod
Uncorrected visual acuity for distance (4m)Six months after implantation

Monocular visual acuity for distance (4m), without any additional correction, using ETDRS vision chart

Best-corrected visual acuity for distance (4m)Six months after implantation

Monocular visual acuity for distance (4m), with the best correction for distance, using ETDRS vision chart

Uncorrected visual acuity for intermediateSix months after implantation

Monocular visual acuity for intermediate distance (60cm), without any additional correction, using ETDRS vision chart

Best-corrected visual acuity for intermediateSix months after implantation

Monocular visual acuity for intermediate distance (60cm), with the best correction for distance, using ETDRS vision chart

Uncorrected visual acuity for nearSix months after implantation

Monocular visual acuity for near distance (40cm), without any additional correction, using ETDRS vision chart

Best-corrected visual acuity for nearSix months after implantation

Monocular visual acuity for near distance (40cm), with the best correction for distance, using ETDRS vision chart

Contrast sensitivity function (CSF)Six months after implantation

CSF with best correction, with and without induced glare, using the Clinical Trial Suite

Defocus curveSix months after implantation

Defocus curve of visual performance varying the stimulus vergence from -4.0 D to +1.0 D in 0.5 D steps with the best correction for distance

Trial Locations

Locations (2)

OftalVist Jerez de la Frontera

🇪🇸

Jerez de la Frontera, Cádiz, Spain

OftalVist Alicante

🇪🇸

Alicante, Spain

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