Comparison of controlled ventilation and non-ventilation during extracorporeal membrane oxygenation (ECMO): Respiratory physiological effects

Not Applicable

Recruiting

• Conditions: J80.0; J80.03

• Registration Number: DRKS00029317
• Lead Sponsor: niversitätsklinikum Freiburg, Klinik für Anästhesiologie und Intensivtherapie

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2022-06-15
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 12

Inclusion Criteria

Age = 18 years
Severe ARDS and treatment with veno-venous ECMO

Exclusion Criteria

Age <18 years, pregnancy, known higher-grade valvular vascular disease (third-grade stenosis or insufficiency), heart failure > NYHA 2, contraindications to EIT measurements (active implants, eg. pacemakers, cardioverters, skin disease or injury to the skin in the position of the EIT electrode-belt), BMI = 35 kg/m^2.

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Relative end-expiratory lung volume, regional ventilation/perfusion ratio (V/Q).<br>

Secondary Outcome Measures

Name	Time	Method
Compliance of the respiratory system, homogeneity or distribution in regional ventilation (indicated by ratio of dorsal to ventral ventilation), PaO2, PaCO2, etCO2, FiO2, FeO2, airway pressure, respiratory gas flow, vital signs.