Cardiorespiratory effects of walking on a lower body positive pressure weight support treadmill in healthy adults

Not Applicable

Conditions: Healthy volunteers

Registration Number: DRKS00022254

Lead Sponsor: BG Klinikum Hamburg

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Pending

Sex: All

Target Recruitment: 40

Inclusion Criteria

Written declaration of consent to participate
- Ages 18-65 years
- Weight 50-120kg

Exclusion Criteria

- Under 18 years
- Over 65 years old
- Under 50kg
- Over 120kg
- Injuries or limitations of the lower extremities
- Cardiological diseases or taking the following medications:
1. Blood pressure medication of any kind (b-blockers, calcium channel blockers, ACE inhibitors, diuretics, sartans, renin inhibitors)
2. Heart failure medication (aldosterone antagonists, ARNI, cardiac glycosides)
3. Blood thinners (Marcumar, factor Xa inhibitors, ASA)
- Respiratory diseases or taking the following medications:
1. Stimulants such as ß2 sympathomimetics
2. Inhaled corticoids
- Acute infections
- condition after Thrombosis or pulmonary embolism
- Muscle disorders
- Neurological diseases

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The aim of this investigation is the measurement of various physiological parameters on a treadmill with weight reduction through positive pressure on the lower body in the anti-gravity treadmill system AlterG (AlterG INC., 48438 Milmont Drive, Fremont, CA 94538, Tel .: 510-270-5900 , www.alter-g.com) in healthy subjects.

Secondary Outcome Measures

Name	Time	Method
The AlterG treadmill uses a lower body inflation chamber in which excess pressure is generated to reduce the weight of the runner. Weight reduction can have a relieving effect on the cardiovascular system and local muscle activation.<br><br>For this purpose, the parameters heart rate and blood pressure (systolic / diastolic), VO2, VCO2, AMV and AF should be determined via spirometry depending on different running speeds at 100% body weight and compared with the same running speeds but different body weight reduction on the AlterG.