A Clinical Study on Warm e tajaweef e anf muzmin (Chronic rhinosinusitis) and the comparative evaluation of Unani formulations in its management.

Department of Moalejat Ajmal Khan Tibbiya CollegeAligarh Muslim University Aligarh1 个研究点分布在 1 个国家目标入组 80 人开始时间: 2025年5月25日最近更新: 2025年5月13日

试验速览

Chronic Rhinosinusitis (CRS) affects 5–15% of the population and is often difficult to treat, leading to repeated antibiotic use, long-term steroid therapy, and multiple sinus surgeries. These treatments carry risks such as antibiotic resistance, steroid side effects, and surgical complications. Approximately 200,000 U.S. adults undergo sinus surgery annually due to failed medical therapy. CRS also results in significant economic burden and negatively impacts quality of life, often more than other chronic diseases.
While Unani medicine does not directly name Chronic Rhinosinusitis, its symptoms align with conditions like Nazla Barid and Nazla Muzmin. Unani treatments, especially using single or compound herbal formulations, are considered safer for long-term use. This research aims to evaluate the efficacy of Mufeed Joshanda in management of Chronic rhinosinusitis and to evaluate the efficacy of Sinugard Granules in management of chronic rhinosinusitis, to compare the efficacy of both unani formulations in management of chronic rhinosinusitis

•Clinically diagnosed patients of chronic Rhinosinusitis of not more than 5 years duration.
•Patients of both sexes.
•Patients in the age group of 15 to 50 years.
•Patients with involvement of any sinus.
•Those who give written consent.
•Patients complaining of post nasal drip -Subjective Parameters Nasal obstruction Nasal discharge Sneezing Headache Post nasal drip Abnormalities of smell Heaviness in head -Objective Parameters Xray PNS (water’s view).

•Patients having history of any surgery of nose or paranasal sinuses Patients with Malignancy of the nose or paranasal sinuses.
•Patients having history of any foreign body in their nose.
•Pregnant & lactating mothers.
•Patients who fail to give consent.
•Patients who fail to follow up..
•patient having history of epistaxis.
•Patient having history of trauma to nose or sinus areas Pregnant & lactating mothers.
•Patients suffering from any congenital or acquired structural abnormality of the nasal cavity.
•Any medical condition where physician feels that participation in the study could be detrimental to patient’s well being.
•Patients of pulmonary koch’s.