NCT01032798已完成1 期
Efficacy and Pharmacokinetics of Liposomal Mepivacaine Formulations in Dentistry
University of Campinas, Brazil2 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2007年5月1日最近更新:
适应症
相关药物
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 发起方
- 入组人数
- 30
- 试验地点
- 2
- 主要终点
- Latency period and duration of anesthesia were assessed by an electrical pulp tester
研究概览
简要总结
This blinded cross-over study aim to evaluate the efficacy and the pharmacokinetics of a previously reported liposome-encapsulated mepivacaine formulations.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Health Services Research
- 盲法
- Triple (Participant, Care Provider, Investigator)
入排标准
- 年龄范围
- 20 Years 至 45 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- 未提供
排除标准
- •Volunteers were free from cardiac, hepatic, renal, pulmonary, neurological, gastrointestinal and haematological diseases, psychiatric disorders and allergy to local anesthetics
结局指标
主要结局
Latency period and duration of anesthesia were assessed by an electrical pulp tester
时间窗: 10 minutes
次要结局
- Plasma concentrations of mepivacaine(0 to 360 minutes after the injection)
研究者
研究点 (2)
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