The efficacy of skin-moisturizing agents for radiation dermatitis and basic information associated with radiation dermatitis

Phase 2

Recruiting

• Conditions: Breast cancer

• Registration Number: JPRN-UMIN000005532
• Lead Sponsor: Department of Radiation Oncology St Luke's international Hospital

Brief Summary

A total of 62 patients were analysed. Before randomization, the affected / contralateral skin water content ratio was 0.97 +/-0.13 at the beginning, 0.79+/-0.15 (p=0.00) at the RT completion, and 0.77 +/-0.15 (p=0.00) two weeks after RT. The difference of skin water content ratio comparing four weeks to two weeks after the completion of RT was 0.242 +/-0.225 in moisturizer group and 0.055 +/- 0.145 in no treatment group (p=0.001); indicating the skin water content was significantly increased in moisturizer group.

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2011-04-29
• Study Completion: 2013-09-09
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: Female
• Target Recruitment: 125

Inclusion Criteria

Not provided

Exclusion Criteria

1. Patients with widespread skin complications 2. Patients who have past history of collagen vascular diseases 3. Patients who were sensitive to heparinoid 4. Patients who were judged unsuitable for this study by the investigator.

Study & Design

• Study Type: Interventional
• Study Design: Not specified