Neurodevelopmental Rehabilitation for Toddlers With Complex Heart Defects
Overview
- Phase
- Phase 2
- Intervention
- Not specified
- Conditions
- Heart Defects
- Sponsor
- The Hospital for Sick Children
- Enrollment
- 20
- Locations
- 1
- Primary Endpoint
- Change from baseline in child's neurodevelopmental status at four months using the Peabody Development Motor Scales
- Status
- Completed
- Last Updated
- 12 years ago
Overview
Brief Summary
The purpose of this project is to investigate the feasibility of using a home-based, parent-delivered model for providing neurodevelopmental rehabilitation programmes to infants who have had surgery for a complex heart defect.
Detailed Description
Neurodevelopmental deficits are a common morbidity among children who receive surgical treatment for complex congenital heart defects in infancy. Over 40% of children with complex heart defects will have neurodevelopmental deficits that persist throughout childhood even after a successful surgical procedure in infancy1. These deficits are typically related to basic motor perceptual motor or visual motor skills. Problems integrating what is seen (visual perceptions) with body movement (motor skills) makes it difficult for children to participate in peer play and limits their ability to succeed in school, thereby having a significant impact on the child's quality of life. Traditional, therapist-delivered rehabilitation programmes to address these delays in neurodevelopment have not previously been attempted. It would be difficult to provide direct rehabilitation programmes to these patients given that their defects are rare and few patients are located within the same geographical area. Home-based, parent-delivered rehabilitation programmes have previously been shown to be effective at improving the motor skills of school-age children with complex heart defects5. Since a home-based parent delivered model would enable the participation of infants regardless of geographic location, the feasibility of using such a model for delivering neurodevelopmental rehabilitation should be investigated.
Investigators
Brian McCrindle
Staff Cardiologist
The Hospital for Sick Children
Eligibility Criteria
Inclusion Criteria
- •Families will be eligible to participate in this study if the child:
- •Had the arterial switch operation (for transposition of the great arteries) or has had a Glenn procedure (for functional single ventricle).
- •Is medically stable for normal infant activities.
- •Is between 12 and 24 months of age in January 2010.
Exclusion Criteria
- •Families will be excluded from study participation if:
- •The child has a recognized syndrome or other disability affecting neurodevelopment.
- •The child has had a medical procedure in the 3 months preceding the baseline study assessment.
- •The cardiologist responsible for the child's care refuses to allow the child's participation.
- •The child performs substantially above age-appropriate developmental milestones during the initial assessment (in which case an intervention is unlikely to have a detectable additional benefit).
Outcomes
Primary Outcomes
Change from baseline in child's neurodevelopmental status at four months using the Peabody Development Motor Scales
Time Frame: Baseline and four months
The Peabody Development Motor Scale has demonstrated validity and reliability for children from birth to 5 years of age. Six subtests (reflexes, stationary, locomotion, object manipulation, grasping, visual-motor integration) yield gross, fine and total motor quotient scores.
Secondary Outcomes
- Parents opinion on the home-based neurodevelopmental rehabilitation programme(at 4 months)
- Research students experience and perception of guiding a home-based, parent-delivered rehabilitation programme(at 4 months)