Endoscopic Common Bile Duct Stones Clearance During Pregnancy

Recruiting

• Conditions: Common Bile Duct Calculi
• Interventions: Other: Endoscopic clearance of common bile duct stones

• Registration Number: NCT06092905
• Lead Sponsor: South Valley University

Brief Summary

Background: Pregnancy is associated with a higher risk of common bile duct stones. Currently Endoscopic Retrograde Cholangiopancreatography (ERCP) is the treatment of choice for symptomatic choledocholithiasis. However, ERCP during pregnancy is associated with hazards of radiation exposure, as well as challenging patient positioning and anesthesia

Detailed Description

This is a retrospective analysis of endoscopic common bile duct stone clearance in pregnant patients with symptomatic choledocholithiasis between June 2015 and June 2023.

Sedation and anesthesia was done by safe medications by senior anesthetist, and the endoscopic procedure was performed in left lateral decubitus instead of prone position. The gravid uterus was kept away from the monopolar electrocautery current pathway. Radiocontrast injection and fluoroscopy was deleted and replaced by trans-abdominal US and endoscopic bile aspiration Data including perioperative outcomes and follow up data will collected, tabulated and analyzed.

Study Timeline

• Study Start: 2023-04-01
• Status Verified: 2023-10
• Study First Submitted: 2023-10-15
• Study First Submitted QC: 2023-10-15
• Last Update Submitted: 2023-10-15
• Study First Posted: 2023-10-23
• Last Update Posted: 2023-10-23
• Primary Completion: 2023-11
• Study Completion: 2023-12

Recruitment & Eligibility

• Status: RECRUITING
• Sex: Female
• Target Recruitment: 30

Inclusion Criteria

• Pregnant women with symptomatic common bile duct stones.

Exclusion Criteria

• Presence of pancreatitis or cholangitis.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Pregnant women with symptomatic common bile duct stones	Endoscopic clearance of common bile duct stones	Pregnant women with symptomatic common bile duct stones

Primary Outcome Measures

Name	Time	Method
Complications	Till one month after delivery.	any perioperative complications as pancreatitis, perforation, bleeding, abortion, preterm labor.

Trial Locations

Locations (1)

Qena Faculty of Medicine, South Valley University Hospitals; 🇪🇬 Qinā, Egypt