Evaluation of Response to CRT

Phase 3

Recruiting

• Conditions: Heart failure.; Heart failure

• Registration Number: IRCT20190210042669N1
• Lead Sponsor: Deputy of Research of Imam Khomeini Hospital in Ahvaz

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 21 May 2019

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

Patients with heart failure CRT candidates
Age over 18 years
The attitude to participate in the study
NYHA Class III-IV
wide QRS and LVEF<35%
Sinusoidal rhythm of the EKG
The presence of MR in the primary eco

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Quality of life assessment. Timepoint: It will be measured before of intervention and 2 to 3 weeks after the intervention. Method of measurement: Quality of life assessment will be done by using the Minnesota Heart Rate Quality of Life Questionnaire (MLHFQ). This questionnaire contains 21 questions and examines the impact of illness and treatment on the daily life of patients. The questionnaire focuses on symptoms such as dyspnea, fatigue, edema, and the psychological state and the effect of the disease on the daily activities.;Electrocardiography. Timepoint: It will be measured before of intervention and 2 to 3 weeks after the intervention. Method of measurement: Clinical variables including QRS duration (ms), PR interval (ms) and HR (b pm) will be measured by electrocardiogram.Other parameters include LV end-systolic volume (ESV), LV end-diastolic volume (EDV) LV ejection fraction (EF), Mitral Regurgitation (MR), Full-volume of LV will measure by echocardiography.

Secondary Outcome Measures

Name	Time	Method
Diabetes. Timepoint: It will be measured before of intervention and 2 to 3 weeks after the intervention. Method of measurement: Parameter of diabetic is measured by glucometer measurement.;Hypertension. Timepoint: It will be measured before of intervention and 2 to 3 weeks after the intervention. Method of measurement: Parameter of hypertension is measured by barometric measurement.;BMI. Timepoint: It will be measured before of intervention and 2 to 3 weeks after the intervention. Method of measurement: Parameter of BMI is measured by scales, weight division by height, measurement.