TCTR20210423001已完成2 期
Effectiveness of zinc supplement in minimal hepatic encephalophathy: A prospective, randomized controlled trial
avamindradhiraj University Research Fund0 个研究点目标入组 69 人开始时间: 2021年4月23日最近更新:
适应症
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 发起方
- 入组人数
- 69
研究概览
简要总结
Significant improvement of NP tests was established in zinc supplement group when compared with placebo (NCT-A p 0.029, NCT-B, p 0.008, SDT, p 0.002 , DST, p below 0.001). Significant improvement of HRQOL assessed by SF-36 score was seen only in the zinc group, p below 0.001. In the zinc supplement group, not only the improvement of psychomotor performance but quality of life were achieved irrespective of baseline zinc level.
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 Years 至 70 Years（—）
- 性别
- All
入选标准
- •1. Minimal hepatic encephalopathy
- •2. cirrhosis
排除标准
- •1.history of overt HE
- •2.gastrointestinal bleeding and spontaneous bacterial peritonitis in past 6 weeks
- •3.neurological diseases causes of impaired cognitive function eg. Parkinson disease, Alzheimer disease
- •4.recent alcohol consumption within 6 weeks
- •5.on medication affecting psychometric performances like benzodiazepines, antiepileptics or psychotropic drugs
- •6.concurrent with hepatocellular carcinoma or active other malignancy
- •7.pregnancy
- •8.blindness
- •9.cannot read and write
研究者
相似试验
已完成
3 期
Effect of Zinc in treatment of PsoriasisPlaque Type Psoriasis with Skin Involvement Under 20%.Small plaque parapsoriasisL41.3IRCT20191022045186N1Ardabil University of Medical Sciences40
已完成
不适用
Efficacy of zinc supplementation on weight and height growth of healthy 9-18 year childremalnutrition.Disease of digestive system, unspecifiedIRCT201305302639N13Sadoughi University of Medical Sciences, Yazd, Iran, Private100
已完成
3 期
Effect of zinc supplementation on the improvement of gastroesophageal reflux symptomsGastroesophageal reflux disease.Gastroesophageal reflux diseaseIRCT201305281155N16Guilan University Medical sciences, gastrointestinal and liver disease research center140
招募中
不适用
Effects of Zinc in the treatment of patients with pulmonary tuberculosisPulmonary tuberculosis.Respiratory tuberculosis, bacteriologically and histologically confirmedIRCT2016110630729N1Zabol University of Medical Sciences and Health Services90
Unknown
不适用
Testing the Effect of Zinc Supplementation to Improve the Treatment Effect of Botulinum Toxin for Oculofacial SpasmHemifacial SpasmBlepharospasmNCT01546805St. Joseph's Healthcare Hamilton40