NCT00006591Unknown不适用
The Safety and Efficacy of a Ritonavir-Enhanced Agenerase Regimen as Salvage Therapy in HIV-Infected Individuals
Gathe, Joseph, M.D.2 个研究点 分布在 1 个国家开始时间: 2001年8月31日最近更新:
适应症
相关药物
试验速览
- 阶段
- 不适用
- 发起方
- 试验地点
- 2
研究概览
简要总结
The purpose of this study is to determine if treatment with an anti-HIV drug containing ritonavir and Agenerase is safe and can lower the level of HIV in the blood in patients who have failed an anti-HIV drug treatment containing nelfinavir.
详细描述
HIV-infected patients will be treated with a ritonavir-enhanced Agenerase regimen.
研究设计
- 研究类型
- Interventional
- 主要目的
- Treatment
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients may be eligible for this study if they:
- •Are 18 years of age or older.
- •Are HIV-positive.
- •Have a viral load (level of HIV in the body) of more than 1,000 copies/ml.
- •Have had more than 12 weeks of prior anti-HIV drug treatment.
- •Have failed a previous anti-HIV treatment containing nelfinavir as the only protease inhibitor.
- •Are responsive to Agenerase.
- •Are able to follow study requirements.
排除标准
- •Patients will not be eligible for this study if they:
- •Are intolerant to ritonavir (an anti-HIV drug).
- •Have or have had problems with absorption.
- •Have liver disease or damage.
- •Have pancreatic disease or damage.
- •Have taken any protease inhibitor other than nelfinavir.
- •Are receiving investigational drugs or devices from another study.
- •Are pregnant or breast-feeding.
- •Currently use triazolam, astemizole, ergot medications, cisapride, midazolam, bepridil, rifampin, terfenadine, or pimozide.
- •Have a bleeding disorder.
- •Have previously been treated with Agenerase.
- •Are receiving nonnucleosides.
研究者
研究点 (2)
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