Evaluation of ultrasonic axillary dissection in preservation of intercostobrachial nerve function and lymphatic sealing in management of axilla in patients with breast cancer: a randomized controlled trial
Phase 3
Completed
- Conditions
- This study includes 40 patients presented with early breast cancer (T1 and T2) under-went BCS or MRM. The patients randomly assigned into 2 groups,group A: subjected to ANLD using Harmonic Focus tooHarmonic,electrocautery,drain volume,axillary numbness
- Registration Number
- TCTR20200903004
- Lead Sponsor
- Faculty of medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
Inclusion criteria
Female patients with early (T1 or T2) cancer breast fit for both BCS and MRM.
Exclusion Criteria
(1) Patients with carcinoma in-situ.
(2) locally advanced breast carcinoma (T3 and T4).
(3) Metastatic carcinoma.
(4) Recurrent breast carcinoma.
(5) Patients who receive neoadjuvant chemotherapy.
(6) Breast sarcomas.
(7) Benign breast lump.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method operation time and blood loss postoperative hospital stay, total drainage volume, mean drain durati 2.8 years time from skin to skin, blood loss by sponge count and weight and suction volume
- Secondary Outcome Measures
Name Time Method Preservation of axillary sensation 2.8 years using a piece of ice and compare the sensation with the other axilla (superficial sensation).
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie intercostobrachial nerve preservation during ultrasonic axillary dissection in breast cancer?
How does ultrasonic axillary dissection compare to traditional methods in preserving lymphatic function and reducing numbness in T1/T2 breast cancer patients?
Are there specific biomarkers that correlate with improved outcomes following Harmonic Focus-assisted axillary dissection in early breast cancer?
What are the potential adverse events associated with ultrasonic axillary dissection using Harmonic Focus technology in breast cancer surgery?
How do combination approaches involving ultrasonic dissection and lymphatic sealing impact axillary management in breast-conserving surgery versus mastectomy patients?