Before-after study of efficacy of morphine for dyspnea in patients with chronic obstructive pulmonary disease
- Conditions
- COPD
- Registration Number
- JPRN-UMIN000015288
- Lead Sponsor
- on-Profit Organization JORTC
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 35
Not provided
1. Patients with contraindication of morphine (ex. allergy for morphine and history of severe adverse effects of morphine) 2. Patients who use opioid. Patients who did not use codein within 3 days before study entry are eligble. 3. Patients with COPD acute exacerbation 4. Patients with active infection that causes dyspnea 5. Patients with lung cancer that causes dyspnea 6. Patients with pneumothorax 7. Patients who uses invasive positive airway pressure ventilation. Patients who uses nasal high flow were not excluded 8. Patients who changed the way of intaking of bronchodilators, corticosteroids, vasodilators and anxiolytics within two days before enrollment of the study 9. Patients who have or had drug abuse or drug dependence 10. Patients who are pregnant or possibly pregnant 11. Patients who are judged to be innapropriate for the study by the physician
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method