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Clinical Trials/CTRI/2025/12/098352
CTRI/2025/12/098352Not yet recruitingPhase 1

“Comparison Of Dexmedetomidine And Dexamethasone As Adjuvant To Ropivacaine In Ultrasound-Guided Erector Spinae Plane Block For Elective Unilateral Open Inguinal Hernia Repair Under Spinal Anaesthesia: A Prospective Randomised Double Blind Study.”

Department Of Anaesthesiology Government Medical College1 site in 1 country100 target enrollmentStarted: December 20, 2025Last updated:

Trial Snapshot

Phase
Phase 1
Status
Not yet recruiting
Sponsor
Enrollment
100
Locations
1

Study Overview

Brief Summary

a study titled “Comparison of Dexmedetomidine and Dexamethasone as adjuvant to Ropivacaine in ultrasound-guided erector spinae plane block for elective unilateral open inguinal hernia repair under spinal anaesthesia: a prospective randomised double blind study” will be carried out in gmc. this study included 100 male patients aged between 18 to 60 years randomly divided into two groups of 50 patients each scheduled for unilateral open inguinal hernia repair under spinal anaesthesia receiving thoracic esp block. group a patients will  receive 18 ml of 0.375% ropivacaine plus 0.5µg/kg of dexmedetomidine diluted in 2ml of normal saline (total 20ml) where as in group b patients will receive 18 ml of 0.375% ropivacaine plus 4 mg of dexamethasone diluted in 2ml of normal saline (total 20ml). parameters such as comparison of vas scores between 2 groups, total duration of analgesia, total rescue analgesic consumption in 24 hours and adverse events like  nausea, vomiting sedation bradycardia will be  noted in our study.

Study Design

Study Type
Interventional
Allocation
Randomized
Masking
Participant and Investigator Blinded

Eligibility Criteria

Ages
18.00 Year(s) to 60.00 Year(s) (—)
Sex
Male

Inclusion Criteria

  • PATIENTS IN THE AGE OF 18 TO 60 YEARS MALE PATIENTS POSTED FOR OPEN INGUINAL HERNIA REPAIR.

Exclusion Criteria

  • Patients with coagulopathies, bleeding diathesis, on anticoagulants,chronic pain treatment and cognitive deficit Patients with known hypersensitivity to study drugs.
  • Patients with infection at the puncture site.

Investigators

Sponsor
Department Of Anaesthesiology Government Medical College
Sponsor Class
Government medical college
Responsible Party
Principal Investigator
Principal Investigator

Redapangu Jhansi

Government Medical College

Study Sites (1)

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