Type 2 Diabetes Mellitus With Obesity and Dyslipidemia Treated by Chinese Herbal Medicine
- Conditions
- Type 2 Diabetes Mellitus in ObeseDyslipidemia Associated With Type II Diabetes Mellitus
- Interventions
- Drug: Chinese herb medicine
- Registration Number
- NCT05072990
- Brief Summary
This study is a retrospective review of participants who visited Department of Endocrinology, Guang'anmen Hospital and accepted traditional Chinese medicine formula for at least sis months, from January 2015 to December 2020. All the participants should be diagnosed as type 2 diabetes mellitus, obesity and dyslipidemia. Therapeutic effect of traditional Chinese medicine will be evaluated based on the changes of blood glucose, body mass index, blood lipids, and blood pressure.
- Detailed Description
The diagnostic criteria for type 2 diabetes mellitus and obesity are based on the Guideline for the prevention and treatment of type 2 diabetes mellitus in China (2020 edition). The diagnostic criteria of dyslipidaemia are based on the Chinese Guidelines on Prevention and Treatment of Dyslipidaemia in Adults (2016, revision edition).
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 95
- Meet at least three of the requirements below; 1) Fasting Plasma Glucose > 6.1 mmol/L or 2-hour Postprandial Blood Glucose > 7.8 mmol/L or diagnosed as type 2 diabetes mellitus; 2) Body Mass Index > 25 kg / m2; 3) Total Cholesterol > 5.2 mmol / L; Or Triglyceride > 1.70 mmol / L; Or Low-Density Lipoprotein > 3.12 mmol / L; Or High-Density Lipoprotein < 1.04 mmol/L. 4) Systolic blood pressure > 130 mmHg or Diastolic blood pressure > 85 mmHg or diagnosed as hypertension;
- Received 6 months of continuous Chinese herbal medicine treatment;
- During the period of receiving Chinese herbal medicine, the patients continued to take western medicine according to the doctor's advice as before.
- During the period of receiving Chinese herbal medicine, diet and exercise continued according to the original routine, and the tests would be reviewed in the same institution.
- Aged 18 to 80 years at the time of their consent;
- Signed informed consent.
- Patients who had serious heart, lung, liver, kidney and brain diseases; serious infectious or hemorrhagic diseases; serious nervous system diseases, mental instability; or could not cooperate with treatment were excluded.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Observational group Chinese herb medicine -
- Primary Outcome Measures
Name Time Method Change from Baseline HbA1c at 3 months, 6 months 0 month, 3 months, 6 months Changes from Baseline Fasting Blood Glucose at 3 months, 6 months 0 month, 3 months, 6 months Changes from Baseline Low Density Lipoprotein at 3 months, 6 months 0 month, 3 months, 6 months Changes from Baseline Triglyceride at 3 months, 6 months 0 month, 3 months, 6 months Changes from Baseline Body Mass Index at 3 months, 6 months 0 month, 3 months, 6 months
- Secondary Outcome Measures
Name Time Method Changes from Postprandial Blood Glucose at 6 months 0 month, 6 months Changes from Total Cholesterol at 6 months 0 month, 6 months Changes from Systolic Blood Pressure at 6 months 0 month, 6 months Changes from High Density Lipoprotein at 6 months 0 month, 6 months Changes from Diastolic Blood Pressure at 6 months 0 month, 6 months
Trial Locations
- Locations (1)
Guang'anmen Hospital, China Academy of Chinese Medical Sciences
🇨🇳Beijing, Beijing, China
Guang'anmen Hospital, China Academy of Chinese Medical Sciences🇨🇳Beijing, Beijing, China