Fluoroscopic Guided Radiofrequency of Genicular Nerves for Pain Alleviation in Chronic Knee Osteoarthritis : A Single-blind Randomized Controlled Trial.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- pain assessment by VAS scale
研究概览
简要总结
Osteoarthritis (OA) affects aged above 45 years. RF has been used for several painful conditions. There have been a few attempts to use RF current for the treatment of painful conditions of joints of the extremities. It was also used for the treatment of painful conditions of the hip joint.
详细描述
Osteoarthritis (OA) is commonest chronic arthritis affecting patients usually aged above 45 years. OA decreased health-related quality of life and increased economic costs. Radiofrequency (RF), was used for the treatment of chronic pain unresponsive to conservative therapies. RF has been used for several painful conditions. There have been a few attempts to use RF current for the treatment of painful conditions of joints of the extremities. It was also used for the treatment of painful conditions of the hip joint.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Investigator)
入排标准
- 年龄范围
- 30 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •chronic arthritis according to the American College of Rheumatology criteria
- •diagnosed radiologically patients in stage 3 and 4, according to the Kellgren-Lawrence classification
排除标准
- •other causes of pain such as radiculopathy, neurological disorders, or intermittent claudication.
- •patients receive intraarticular steroid or hyaluronic acids during previous three months.
- •patients did previous knee surgery.
- •Patients with general contraindication to the application of invasive intervention such as hemorrhage, coagulation disorder, systemic infection or local infection.
- •patients with other connective tissue disease affecting the knee. And 6-psychiatric disorders.
研究组 & 干预措施
radiofrequency group
radiofrequency was done in the three genicular nerves upper medial and upper lateral and lower medial
干预措施: radiofrequency (Procedure)
conventional group
the patients received conventional paracetamol and non steroidal antiinflammatory
干预措施: Paracetamol (conventional) (Drug)
conventional group
the patients received conventional paracetamol and non steroidal antiinflammatory
干预措施: Ketorolac Tromethamine (conventional) (Drug)
结局指标
主要结局
pain assessment by VAS scale
时间窗: 6 months
assessing pain by VAS scale
次要结局
- patient satisfaction by Likert scale(6 months)
- patient disability by Western Ontario McMaster Universities OA index(6 months)
研究者
Emad Zarief , MD
Lecturer of Anesthesia and ICU
Assiut University