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Biobank 3 Hoorn Diabetes Care System Cohort follow up 2023

Recruiting
Conditions
Diabetes
insulin insensitivity
10018424
10040998
10057166
Registration Number
NL-OMON53604
Lead Sponsor
Amsterdam UMC
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
Not specified
Target Recruitment
2500
Inclusion Criteria

- All adult newly diagnosed patients with T2D in the Hoorn DCS, who have not
yet been asked to participate in research;
- All DCS participants with T2D who have previously provided informed consent
to be contacted for research.

Exclusion Criteria

• Unable to give written informed consent.
• Serious mental impairment i.e. preventing to understand the study protocol /
aim.

Study & Design

Study Type
Observational invasive
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
<p>The primary endpoint are diabetes progression and incident diabetes<br /><br>complications, including microvascular complications (foot complications,<br /><br>retinopathy, nephropathy), macrovascular complications (cardiovascular disease,<br /><br>including myocardial infarction, angina pectoris, heart failure, stroke,<br /><br>transient ischaemic attack and peripheral arterial disease) as well as<br /><br>all-cause and cause-specific mortality. </p><br>
Secondary Outcome Measures
NameTimeMethod
<p>Secondary endpoints include diabetes progression measured as anthropometrics,<br /><br>metabolic status, prevalence and severity of non-alcoholic fatty liver disease<br /><br>(NAFLD), medication use, psychological complications and quality of life. </p><br>
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