A 12-week, randomized, double-blind, placebo-controlled clinical trial to evaluate the efficacy and safety of Angelica gigas Nakai extract(AGE232) on improvement of blood flow
- Conditions
- Not Applicable
- Registration Number
- KCT0008623
- Lead Sponsor
- Astrogenesis
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 100
1) Male or female subjects aged from 25 to 70 years old
2) Those who satisfy 3 or more criteria
? Subjects who 200~239 mg/dL of fasting total-cholesterol
? Subjects who130~159 mg/dL of fasting LDL-cholesterol
? Subjects who 100~125 mg/dL of fasting blood sugar
? Subjects who 120~139 mmHg of systolic blood pressure
? Subjects who BMI 25~29.9 kg/m2 of BMI
? Subjects who male 0.9, female 0.85 of WHR
1) Subjects who have disorders in platelet function and platelet coagulation
2) Subjects who BMI 25~29.9 kg/m2 of BMI
3) Subjects who have taken medications or dietary supplements related to platelet function, blood circulation improvement, and hyperlipidemia within 4 weeks before study enrollment
4) Subjects who Alcoholism (21 units/week) or substance abuse or dependence
5) Subjects who have an overreaction to the ingredients contained in the human body application test product
6) Women undergoing hormone replacement therapy
7) Participation in other clinical trials within the previous three months
8) Subjects who are pregnant and breastfeeding female
9) Subjects who do not perform adequate contraception in the urban eligible women (except the woman who undergo sterilization operation)
10) Subject who was deemed inappropriate to participate in this clinical trial by the research director due to other reasons including screening test
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method platelet aggregation(PFA);Peripheral arterial tonometry
- Secondary Outcome Measures
Name Time Method Oxidized LDL;Thromboxane B2, e-NOS, COX-2;TC, TG, HDL-C, LDL-C