Metoclopramide versus ondansetron for preventing nausea and vomiting after cesarean sectio

Phase 3

• Conditions: Post-operative nausea and vomiting.; Nausea with vomiting, unspecified; R11.2

• Registration Number: IRCT20220502054722N1
• Lead Sponsor: Vice-Chancellery for Research, Hormozgan University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 7 February 2023

Recruitment & Eligibility

• Status: Complete
• Sex: Female
• Target Recruitment: 150

Inclusion Criteria

Age of 18-40 years old
ASA class I and II
Term and singleton pregnancy
Candidacy for elective cesarean section

Exclusion Criteria

Contraindications of spinal anesthesia
History of postoperative nausea and vomiting
History of severe motion sickness
Gestational hypertension
History of opioid abuse
Preeclampsia
History of taking antiemetics one week before surgery
Less than six hours fasting before surgery
Emergency cesarean section

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Postoperative nausea and vomiting. Timepoint: At 1, 2, 4, and 6 hours after surgery. Method of measurement: Number of episodes and severity using a visual analog scale.

Secondary Outcome Measures

Name	Time	Method
Hypotension. Timepoint: Before surgery and at 1, 2, 4, and 6 hours after surgery. Method of measurement: Using a standard sphygmomanometer.;Diastolic blood pressure. Timepoint: Before surgery and at 1, 2, 4, and 6 hours after surgery. Method of measurement: Using a standard sphygmomanometer.;Heart rate. Timepoint: Before surgery and at 1, 2, 4, and 6 hours after surgery. Method of measurement: Counting the heart beat per minute.