Bright Light: A Novel Treatment for Anxiety
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 入组人数
- 33
- 试验地点
- 2
- 主要终点
- Hamilton Anxiety
研究概览
简要总结
The primary aim of this research was to examine the influence of bright light on anxiety in high-anxious young adults. In an acute exposure study, participants were randomly assigned to 45 min of either (1) bright light (3,000 lux) or (2) a placebo inactivated negative ion generator. Treatments were initiated ≤1 hr after awakening. At 10 min before and 30 min after the treatments, state anxiety, mood, and blood pressure were assessed.
Following the acute exposure study, participants performed a 5-week study. Following a a 1-week baseline, participants were randomly assigned to four weeks of daily exposure to either (1) bright light (45 min/day; 3,000 lux) or (2) placebo inactivated negative ion generator, which were initiated ≤1 hr after awakening. Before and after the experiment, clinical ratings were conducted with the Hamilton Anxiety Scale, the Hamilton Depression Scale, and the Clinical Global Impressions scale (CGI). Following baseline, and following each week of treatment, blood pressure, as well as questionnaires for state anxiety, depression, mood, sleep, and side effects were assessed.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 35 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Having a level of trait anxiety [Spielberger State-Trait Anxiety Inventory (Form Y1)]{23642} that was ≥ the 75th percentile for their age (i.e., ≥ 46 and ≥ 44 for women and men, respectively)
排除标准
- •Current treatment for anxiety or depression;
- •History of bipolar disorder, mania, or psychotic disorders;
- •History of winter depression, which might bias towards positive response to light;
- •Hypertension;
- •Ophthalmic abnormalities; and
- •Usual exposure to high levels of light such that the intervention would add little to usual exposure.
结局指标
主要结局
Hamilton Anxiety
时间窗: 5 weeks
Hamilton Anxiety Questionnaire
Spielberger State Anxiety Inventory
时间窗: 5 weeks
state anxiety questionnaire
次要结局
- Beck Depression Inventory(5 weeks)
- Pittsburgh Sleep Quality Inventory(5 weeks)
研究者
Shawn Youngstedt
Assistant Professor
University of South Carolina