CTRI/2020/07/026754
Completed
未知
Retrospective assessment of outcomes in clinical management of patients with Cryptorchidism with Congenital Hypogonadotropic Hypogonadism: Single Center experience and review of literature
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Health Condition 1: E236- Other disorders of pituitary gland
- Sponsor
- Department of Endocrinology
- Enrollment
- 6
- Status
- Completed
- Last Updated
- 4 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Male Patients with CHH with cryptorchidism, unilateral or bilateral.
- •The diagnosis of CHH was based on the following criteria:
- •(1\)Clinical Phenotype\- Unilateral or bilateral cryptorchidism with micropenis since birth
- •(2\) Evidence of CHH based on 1 of the following criteria
- •a) Age \> 14 years with absence of secondary sexual characters with low or normal gonadotropins along with low Inhibin B and Testosterone for age
- •b) clinical history of anosmia/hyposmia and/or MRI Pituitary showing hypoplasia / aplasia of olfactory bulbs and sulci
- •c) Genetic analysis conducive with CHH
- •d) Syndromic etiology with CHH as a component
- •3\) Normal levels of other pituitary hormones
- •4\) Absence of any structural lesions on imaging (MRI) of brain
Exclusion Criteria
- •Idiopathic cryptorchidism or cryptorchidism of any etiology other than CHH.
Outcomes
Primary Outcomes
Not specified
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