Skip to main content
MedPath Trial logoMedPath TrialMedPath Trial Home
Clinical Trials/NCT07590362
NCT07590362RecruitingNot Applicable

Diaphragmatic Rapid Shallow Breathing Index (D-RSBI) Versus Traditional Rapid Shallow Breathing Index (RSBI) for Prediction of Weaning Success From Mechanical Ventilation in COPD Patients

Sohag University1 site in 1 country100 target enrollmentStarted: April 15, 2026Last updated:
Share to TwitterShare to FacebookShare to LinkedInShare to Reddit

Trial Snapshot

Phase
Not Applicable
Status
Recruiting
Enrollment
100
Locations
1
Study OverviewStudy DesignEligibility CriteriaInvestigatorsSitesRecords & IdentifiersSimilar Trials

Study Overview

Brief Summary

This prospective observational cohort study aims to compare the predictive accuracy of diaphragmatic rapid shallow breathing index (D-RSBI) versus traditional rapid shallow breathing index (RSBI) for predicting weaning success from invasive mechanical ventilation in COPD patients. Diaphragmatic ultrasound measurements will be performed during spontaneous breathing trials, and patients will be followed for 72 hours after extubation to assess weaning outcomes.

Study Design

Study Type
Observational
Observational Model
Cohort
Time Perspective
Prospective

Eligibility Criteria

Ages
18 Years to — (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • •Mechanically ventilated COPD patients fulfilling standard weaning readiness criteria.
  • •Invasive mechanical ventilation for more than 24 hours before spontaneous breathing trial.
  • •Hemodynamically stable without significant vasopressor support.
  • •Adequate oxygenation with FiO2 ≤ 0.5 and PEEP ≤ 8 cmH2O .
  • •Preserved mental status and ability to initiate spontaneous breathing.
  • •Successful tolerance of spontaneous breathing trial conducted on CPAP mode with pressure support ≤ 8 cmH2O.

Exclusion Criteria

  • •Refusal of consent
  • •Neuromuscular disease, phrenic nerve palsy, or diaphragmatic paralysis.
  • •Large pneumothorax or pathology interfering with ultrasound assessment.
  • •Terminal extubation.
  • •Recent major thoracic surgery.
  • •Poor sonographic window despite repeated attempts.

Investigators

Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Ahmed Atef Mohamed

Resident of Anesthesia, ICU and Pain Management faculty of medicine Sohag University

Sohag University

Study Sites (1)

Loading locations...

Similar Trials

Not yet recruiting
Not Applicable
This study aims to find the use of Ultrasonographic Diaphragmatic parameter in the weaning of mechanical ventilation from a patient
CTRI/2024/07/069810SHRI BALAJI INSTITUTE OF MEDICAL SCIENCE100
Not yet recruiting
Not Applicable
Compare two parameters,diaphragmatic rapid shallow breathing index and diaphragmatic thickness fraction,to predict successfully taking out from ventilator support in critically ill patient.
CTRI/2024/08/072124Pt B D Sharma PGIMS Rohtak44
Recruiting
Not Applicable
The Rapid Shallow Breathing Index (RSBI) is a Widely Used Predictor for Weaning Patients From Mechanical Ventilation This Study Aims to Determine the Predictive Value of RSBI Measurements for Extubation Success in Mechanically Ventilated ICU Patients
NCT07467265Ain Shams University70
Not yet recruiting
Not Applicable
identifying Extubation failure in ICU Patients Using Occlusion Airway Pressure (P0.1) Compared to Rapid Shallow Breathing Index (RSBI)
CTRI/2025/03/081652Prajna N S77
Not yet recruiting
Not Applicable
To find effect of belly breathing and Jacobsons relaxation technique in female school teachers with chronic workplace stress
CTRI/2024/05/068086Physiotherapy School and centre Seth G S Medical college Mumbai33