Ultrasound Guided Thoracic Paravertebral Blocks: An Effective Pain Control in Percutaneous Radiofrequency Ablation of Hepatic Tumors
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 35
- 试验地点
- 1
- 主要终点
- pain score at recovery room both at rest and movement (cough)
研究概览
简要总结
Patients undergo percutaneous radiofrequency ablation of hepatic tumors at Siriraj hospital normally receive only intravenous sedative drugs which sometimes can not provide effective pain control.
TPVB is suitable for unilateral operations. And it is increasing popular nowadays because of using ultrasound guided which make it is more reliable and has less side effects especially the severe one such as pneumothorax. To cover all nerve supply liver, we decided to use right TPVB at T5-6, T7-8, and T9-10.
The aim of this study is to prove that TPVB can provide an effective pain control for patients undergo liver RFA both at rest and movement (cough). We are going to measure the pain score at recovery room and the effective pain control means patients has mild pain (pain score less </= 3 and do not ask for analgesic drugs).
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age > 18 years
- •Patients undergo percutaneous radiofrequency ablation for liver tumors
- •ASA classification 1-3
排除标准
- •Psychiatric illness
- •Chronic abdominal pain > 1 week
- •Regular analgesic drugs use
- •Infection at back (Block area)
- •Severe spinal deformity
- •PT > 16 sec, aPTT > 32, platelet < 50,000/cumm
研究组 & 干预措施
0.5% marcaine 20ml
3 levels ultrasound guided thoracic paravertebral blocks at T5-6, T7-8 and T9-10 (total 0.5% marcaine 20ml)
干预措施: 0.5% marcaine 20ml (Drug)
结局指标
主要结局
pain score at recovery room both at rest and movement (cough)
时间窗: Up to 24 hours
All patients at recovery room has mild pain (pain score \</= 3) and do not need any rescue analgesic drugs.
次要结局
- Distribution of local anesthetic drugs after performing ultrasound guided TPVB at T5-6, T7-8 and T9-10.(After performing TPVB at 5, 10, 20 and 30 minutes.)