Effect of a diabetes-specific oral nutritional supplement (ONS) vs. standard ONS on the postprandial glucose response in adults with type 2 diabetes with (risk of) malnutrition.
Recruiting
- Conditions
- Diabetes Mellitus type 2
- Registration Number
- NL-OMON24556
- Lead Sponsor
- Danone Research - Centre for Specialised Nutrition
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 20
Inclusion Criteria
1. Age ≥ 18 yrs;
2. (At risk of) malnourishment, based on the presence of one or more of the following criteria:
Exclusion Criteria
1. Any gastrointestinal disease that interferes with bowel function and nutritional intake (i.e. diabetes related diarrhoea secondary to neuropathy, diarrhoea due to chronic inflammatory bowel disease, gastroparesis);
2. Any known severe disease, i.e.:
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 4-hour postprandial blood glucose response after consumption of diabetes-specific or standard ONS (iAUC0-4h).
- Secondary Outcome Measures
Name Time Method 1. 4-hour postprandial responses after consumption of diabetes-specific or standard ONS:<br /><br>A. Blood glucose levels (iAUC0-4h) (serving size);<br /><br>B. Blood insulin levels (iAUC0-4h);<br /><br>C. Blood glucagon levels (iAUC0-4h).<br /><br>2. Postprandial peak blood glucose, insulin and glucagon levels;<br /><br>3. Postprandial delta peak blood glucose, insulin and glucagon levels.