Vascular regeneration therapy using autologous peripheral blood mononuclear cells for refractory skin ulcer associated with connective tissue diseases and vasculitis - PBMC transplantation for ulcer associated with connective tissue diseases and vasculitis

Kumamoto University0 sites10 target enrollmentNovember 23, 2016

Overview

Phase: Phase 1
Intervention: Not specified
Conditions: Patients with refractory skin ulcers resistant to normal treatment, mainly caused by connective tissue diseases and vasculitis
Sponsor: Kumamoto University
Enrollment: 10
Status: Completed
Last Updated: 2 years ago

No summary available.

Registry

who.int

Start Date

November 23, 2016

End Date

August 24, 2022

Last Updated

2 years ago

Study Type

Interventional

Sex

All

Sponsor

•1\) Patients whose have severe hypersensitivity or history of side effects to aphaeresis 2\) Patients whose have malignant tumor or history of malignancy within the past 5 year 3\) Patients whose have suffering acute myocardial infarction, unstable angina pectoris, myocarditis or cerebral infarction within 3 months 4\) Patients whose circulatory dynamics are remarkably unstable due to severe heart failure, arrhythmia and the like (in the case where it is judged that it is desirable for cardiovascular medical specialists to avoid this treatment) 5\) Patients with active infection 6\) Patients whose are pregnant or might be pregnant 7\) Patients with proliferative diabetic retinopathy (untreated, medium\-term and late proliferative retinopathy) the end of treatment example is excluded 8\) Patients with less than serum albumin 2 mg/dL 9\) Patients whose are judged inappropriate for this trial by their attending physician