Memantine in treatment of major depressio
Phase 2
- Conditions
- Major Depressive disorder.Depressive episode
- Registration Number
- IRCT201502161556N72
- Lead Sponsor
- Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
presence of Major Depressive Disorder based on DSM-IV criteria; baseline Hamilton Depression Rating Scale (HAM-D) (17-item) score of at least 22; signing informed consent. Exclusion criteria: presence of psychosis; any diagnosis in Axis I and II; receiving psychotropic medications; receiving any antidepressants during past one month or ECT during past two months; presence of hypo or hyperthyroidism or cardiovascular problems; pregnancy and breast feeding.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Severity of depression. Timepoint: Baseline and weeks 2-4-6 after beginig of treatment. Method of measurement: By Hamiltion Depression Rating Scale 17-Item.
- Secondary Outcome Measures
Name Time Method