Comparing the effect of probiotic and conventional yoghurt consumption on metabolic status and serum hs-CRP level, leptin and paraoxonase 1 enzyme activity in patients with non-alcoholic fatty liver disease (NAFLD)

Vice-chancellor for research-Tabriz University of Medical Science0 个研究点目标入组 70 人开始时间: 待定最近更新: 2018年2月22日

试验速览

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•patients who agree to participate in the study; women aged 20-50 years (premenopausal) and in men 20-65 years; BMI range between 25 to 40 kg/ m2 and suffering from nonalcoholic fatty liver disease.
•Exclusion criteria: suffering from gastrointestinal disease, diabetes and rheumatoid arthritis; receiving antibiotics during the two weeks before and during the study; follow the diet and weight loss; receiving supplements of vitamins, antioxidants, fiber and omega-3 within 3 weeks before baseline and during the study; presence of pregnancy or lactation or menopause; taking contraceptive drugs; liver transplantation; alcohol intake; any cause of chronic liver disease other than NAFLD, such as testing positive for hepatitis B, hepatitis C and autoimmune hepatitis – Immune; history of cancer and treatment; performing a complete intravenous feeding; rapid weight loss; cut part of the intestine and gastropathy; drugs such as corticosteroids, amiodarone, tamoxifen, cyclins, perhexiline, methotrexate, aspirin and hydralazine; presence of inherited Hemochromatosis (transferrin saturation greater than 45%) and Wilson's disease; Cholestatic liver disease; advanced liver disease; heart failure; thyroid (abnormal TSH) and renal disease; gastric bypass surgery and cachexia.

发起方

Vice-chancellor for research-Tabriz University of Medical Science