Genetic origin of Dupuytren*s disease and associated fibromatosis - GODDAF

niversitair Medisch Centrum Groningen0 个研究点目标入组 600 人开始时间: 待定最近更新: 2024年5月13日

适应症

试验速览

暂无简介。

•Gene expression study:
•1.Clinically confirmed diagnosis of Dupuytren*s, Peyronie*s or Ledderhose*s disease
•2.Patient for which selective fasciectomy or plaque excision/biopsy is part of standard treatment
•3.Evident cord AND node at physical examination (only for patients with Dupuytren*s disease)
•4. Age >= 18;Gene expression study Dupuytren controls:
•1.Confirmed diagnosis of Carpal Tunnel Syndrome
•2.Patient for which carpal tunnel release is part of standard treatment
•3.Age >= 18;Gene expression study Peyronie controls:
•1.Patient receiving penile prosthesis implants for erectile dysfunction or patient having penis amputation
•2.Age >= 18;Pedigree analysis and association study:
•1.Clinically confirmed diagnosis of Dupuytren*s disease, Peyronie*s disease or Ledderhose*s disease
•2.Having relatives with one of these diseases (only for pedigree analysis)
•3.Age >= 18;Pedigree analysis family of proband:
•1. Age >= 18;Association study controls:
•1.Age >= 18

•Gene expression study:
•1.Post-surgical recurrence
•2.Patients unfit to undergo surgery;Gene expression study Dupuytren controls:
•1.Diagnosis of Dupuytren*s, Peyronie*s or Ledderhose*s disease or a positive family history for one of these diseases;Gene expression study Peyronie controls:
•1.Diagnosis of Dupuytren*s, Peyronie*s or Ledderhose*s disease or a positive family history for one of these diseases;Pedigree analysis and association study:
•None;Pedigree analysis family of proband:
•None;Association study controls:
•1.Diagnosis of Dupuytren*s disease, Peyronie*s disease or Ledderhose*s disease or a positive family history for one of these diseases

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