A clinical study to find out ability of Polymerase chain reaction test in detecting infection in neonates
Not Applicable
- Conditions
- Health Condition 1: null- health care associated infections in neonates
- Registration Number
- CTRI/2018/04/013358
- Lead Sponsor
- Vivek Raju
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Neonates with features of health care associated infections if both culture and PCR is sent before starting or changing antibiotics are included
Exclusion Criteria
1.surgical condition
2. Antibiotic change based on a culture report
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The microbe detection rate, measured as proportion of sample reported positive (on blood / CSF culture and PCR) out of total samples sentTimepoint: within 5 days of suspected infection
- Secondary Outcome Measures
Name Time Method 1.Profile of microbes detected by blood / CSF culture and PCR <br/ ><br>2.Incidence of fungal sepsis <br/ ><br>3.Antibiotic resistance pattern <br/ ><br>4.Increase in proportion of microbe detected by â??blood/ CSF culture and PCRâ?? among babies suspected to have HAI when compared with historical controls when blood culture alone was used. <br/ ><br>Timepoint: In an episode of suspected infection