Investigating the effect of Shirazi thyme essential oil on the clinical symptoms of patients with gastroesophageal reflux

Phase 3

Recruiting

• Conditions: Gastroesophageal reflux disease.; Gastro-esophageal reflux disease without esophagitis; K21.9

• Registration Number: IRCT20240116060709N1
• Lead Sponsor: Gonabad University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 6 March 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 70

Inclusion Criteria

Willingness to attend the study
Patients with second grade reflux severity (patients who were not able to resolve their symptoms with lifestyle changes alone)
Age 20 to 60 years
Absence of pregnancy and breastfeeding
Absence of allergy to thyme
Not having diabetes
No previous upper gastrointestinal surgery
Absence of positive and clinically significant gastrointestinal bleeding in the last three months
Absence of proven diseases such as: bleeding disorder, Barrett's Esophagus,esophageal varices, duodenal/stomach ulcer and upper gastrointestinal tract malignancy
Able to read, understand and complete the questionnaire

Exclusion Criteria

Reluctance to continue research
Hospitalization during the study
Not using gastrolith capsules for more than 5 days

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Percentage of people with second-degree gastroesophageal reflux (patients who were not able to resolve their symptoms only by lifestyle changes). Timepoint: Before the intervention and 45 days after the intervention. Method of measurement: Reflux disease questionnaire.