Topography Versus Non-Topography-Guided Photorefractive Keratectomy With Corneal Cross-Linking Variations in Keratoconus
试验速览
- 阶段
- 不适用
- 入组人数
- 38
- 试验地点
- 1
- 主要终点
- visual acuity
研究概览
简要总结
To our knowledge, this study is one of the first to compare the visual results of non-topography-guided and topography-guided photorefractive keratectomy (PRK) applying sequential and simultaneous corneal cross-linking (CXL) treatment for keratoconus. Considering recent advances in cross-linking and imaging in keratoconus, the outcomes of this study can lead us to several non-invasive algorithm management options.
详细描述
Interventional and comparative prospective study: Sixty-nine eyes (38 patients) suffering from keratoconus (stages 1-2 Amsler-Krumeich classification) were divided into four groups. The four groups underwent topography- and non-topography-guided PRK with sequential and simultaneous CXL. The main outcome measures were pre- and postoperative uncorrected distance visual acuity (UDVA), best corrected distance visual acuity (CDVA), manifest refraction, contrast sensitivity, and keratometry.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Sequential
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 34 Years 至 41 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •age 34 (range from 34 to 41)
- •stable corneal topography and refraction for at least six months
- •estimated residual bed thickness of >410 µm
- •presence of macular or retinal disease,
- •history of recurrent corneal erosions
- •anterior segment abnormalities
- •unstable refractive error
- •post-surgically residual stromal bed thickness of under 350 mm
- •autoimmune disease
- •collagen vascular disease
- •immunosuppressive therapy or current use of systemic corticosteroids
- •diabetes mellitus
- •pregnancy
- •lactation
排除标准
- 未提供
研究组 & 干预措施
Photorefractive keratectomy in mile keratoconus
Photorefractive keratectomy in mile keratoconus type of corneal surface ablation in for correct refractive error
干预措施: Photorefractive keratectomy in mile keratoconus (Procedure)
结局指标
主要结局
visual acuity
时间窗: 3 months
Visual acuity (VA) commonly refers to the clarity of vision
次要结局
未报告次要终点
研究者
farinaz doroodgar
Ophthalmologist
Shahid Beheshti University