The Johns Hopkins Heartburn Center Registry

• Conditions: Barrett Esophagus; Laryngopharyngeal Reflux; Gastroesophageal Reflux Disease; Esophagitis

• Registration Number: NCT03853772
• Lead Sponsor: Johns Hopkins University

Brief Summary

A multi-center, multi-year registry of patients with gastroesophageal reflux disease (GERD) undergoing diagnostic evaluation and/or treatment of GERD and associated diseases and complications.

Detailed Description

This registry is a prospective, multicenter registry of patients undergoing diagnostic evaluation and/or treatment of gastroesophageal reflux disease and associated diseases and complications.

Patients who are eligible will have disease and therapy-specific data collected throughout treatment and long-term (5-year) follow-up.

Electronic data capture via REDCap will be utilized for all sites.

Study Timeline

• Study First Submitted: 2019-02-22
• Study First Submitted QC: 2019-02-22
• Study First Posted: 2019-02-26
• Study Start: 2019-04-27
• Status Verified: 2025-03
• Last Update Submitted: 2025-03-10
• Last Update Posted: 2025-03-11
• Primary Completion: 2025-12
• Study Completion: 2025-12

Recruitment & Eligibility

• Status: ENROLLING_BY_INVITATION
• Sex: All
• Target Recruitment: 2000

Inclusion Criteria

• Referred GERD patients willing to participate in long term follow-up (5 years)

Exclusion Criteria

• Potential participants will be excluded if unwilling or unable to complete surveillance questionnaires through this registry

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Demographic and clinical data obtained via chart review and questionnaires	5 years	Establish a registry with collected data related to patients undergoing diagnostic evaluation and treatment of GERD and its associated diseases in multiple academic and community settings.

Trial Locations

Locations (9)

UCI-Irvine; 🇺🇸 Orange, California, United States

The Matagorda Regional Medical Group; 🇺🇸 Bay City, Texas, United States

UT Health; 🇺🇸 Houston, Texas, United States

Johns Hopkins Hospital; 🇺🇸 Baltimore, Maryland, United States

Weill Cornell; 🇺🇸 New York, New York, United States

UNRMed-University of Nevada, Reno; 🇺🇸 Reno, Nevada, United States

Geisinger; 🇺🇸 Danville, Pennsylvania, United States

Fox Valley Surgical Associates; 🇺🇸 Appleton, Wisconsin, United States

Mayo Clinic; 🇺🇸 Rochester, Minnesota, United States