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Quantitative CT Imaging Parameters for Assessing Hepatic Steatosis in CHB

Not yet recruiting
Conditions
Chronic Hepatitis B
Steatosis of Liver
Fibrosis and Cirrhosis of Liver
Registration Number
NCT06616103
Lead Sponsor
Seoul National University Hospital
Brief Summary

This study aims to evaluate diagnostic performance of CT attenuation parameters acquired using deep learning algorithm in assessing hepatic steatosis and fibrosis.

Detailed Description

Not available

Recruitment & Eligibility

Status
NOT_YET_RECRUITING
Sex
All
Target Recruitment
111
Inclusion Criteria
  • chronic hepatitis B
  • no chronic liver disease other than chronic hepatitis B
  • Body mass index >= 23
Exclusion Criteria
  • pregnant women
  • unable to perform MRI examinations due to claustrophobia or metallic foreign body
  • suspicious hepatic malignancy on previous imaging studies
  • history of local treatment for hepatic lesions
  • history of surgery or catheter insertion of liver or spleen

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
diagnostic performance of CT attenuatio parameters in assessing hepatic steatosis and fibrosisAt the time of enrollment

diagnostic performance of CT attenuatio parameters in assessing hepatic steatosis and fibrosis using MRI-PDFF and MR elastography as reference standards

Secondary Outcome Measures
NameTimeMethod
Consistency between MRI-derived body composition data and CT-derived dataAt the time of enrollment

Consistency between MRI-derived body composition data and CT-derived data using automated 3D organ segmentation algorithm

Trial Locations

Locations (1)

Seoul National University Hospital

🇰🇷

Seoul, Korea, Republic of

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