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Clinical Trials/NCT06616103
NCT06616103
Not yet recruiting
Not Applicable

Utility of Quantitative Imaging Parameters from Deep Learning-based CT Segmentation in Assessing Hepatic Steatosis and Fibrosis in Chronic Hepatitis B: a Prospective Study Using MRI As the Reference Standard

Seoul National University Hospital1 site in 1 country111 target enrollmentSeptember 26, 2024

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Chronic Hepatitis B
Sponsor
Seoul National University Hospital
Enrollment
111
Locations
1
Primary Endpoint
diagnostic performance of CT attenuatio parameters in assessing hepatic steatosis and fibrosis
Status
Not yet recruiting
Last Updated
last year

Overview

Brief Summary

This study aims to evaluate diagnostic performance of CT attenuation parameters acquired using deep learning algorithm in assessing hepatic steatosis and fibrosis.

Registry
clinicaltrials.gov
Start Date
September 26, 2024
End Date
August 31, 2025
Last Updated
last year
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Jeongin Yoo

Clinical assistant professor

Seoul National University Hospital

Eligibility Criteria

Inclusion Criteria

  • chronic hepatitis B
  • no chronic liver disease other than chronic hepatitis B
  • Body mass index \>= 23

Exclusion Criteria

  • pregnant women
  • unable to perform MRI examinations due to claustrophobia or metallic foreign body
  • suspicious hepatic malignancy on previous imaging studies
  • history of local treatment for hepatic lesions
  • history of surgery or catheter insertion of liver or spleen

Outcomes

Primary Outcomes

diagnostic performance of CT attenuatio parameters in assessing hepatic steatosis and fibrosis

Time Frame: At the time of enrollment

diagnostic performance of CT attenuatio parameters in assessing hepatic steatosis and fibrosis using MRI-PDFF and MR elastography as reference standards

Secondary Outcomes

  • Consistency between MRI-derived body composition data and CT-derived data(At the time of enrollment)

Study Sites (1)

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