Quantitative CT Imaging Parameters for Assessing Hepatic Steatosis in CHB

Not yet recruiting

• Conditions: Chronic Hepatitis B; Steatosis of Liver; Fibrosis and Cirrhosis of Liver

• Registration Number: NCT06616103
• Lead Sponsor: Seoul National University Hospital

Brief Summary

This study aims to evaluate diagnostic performance of CT attenuation parameters acquired using deep learning algorithm in assessing hepatic steatosis and fibrosis.

Detailed Description

Not available

Study Timeline

• Status Verified: 2024-09
• Study First Submitted: 2024-09-19
• Study First Submitted QC: 2024-09-24
• Last Update Submitted: 2024-09-24
• Study Start: 2024-09-26
• Study First Posted: 2024-09-27
• Last Update Posted: 2024-09-27
• Primary Completion: 2025-08-31
• Study Completion: 2025-08-31

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 111

Inclusion Criteria

• chronic hepatitis B
• no chronic liver disease other than chronic hepatitis B
• Body mass index >= 23

Exclusion Criteria

• pregnant women
• unable to perform MRI examinations due to claustrophobia or metallic foreign body
• suspicious hepatic malignancy on previous imaging studies
• history of local treatment for hepatic lesions
• history of surgery or catheter insertion of liver or spleen

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
diagnostic performance of CT attenuatio parameters in assessing hepatic steatosis and fibrosis	At the time of enrollment	diagnostic performance of CT attenuatio parameters in assessing hepatic steatosis and fibrosis using MRI-PDFF and MR elastography as reference standards

Secondary Outcome Measures

Name	Time	Method
Consistency between MRI-derived body composition data and CT-derived data	At the time of enrollment	Consistency between MRI-derived body composition data and CT-derived data using automated 3D organ segmentation algorithm

Trial Locations

Locations (1)

Seoul National University Hospital; 🇰🇷 Seoul, Korea, Republic of