Effects of kiwifruit extracts on constipation and gut discomfort

Completed

• Conditions: Bowel discomfort; Constipation – defined as having less than 3 bowel movements per week; Oral and Gastrointestinal - Normal oral and gastrointestinal development and function

• Registration Number: ACTRN12613001163796
• Lead Sponsor: ew Zealand Extracts Ltd

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2013-10-21
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

Self reported as healthy
Male/Female
20-65 yrs
Suffer constipation and bowel discomfort

Exclusion Criteria

Significant GI disease including IBD, Crohn’s disease, ulcerative colitis, coeliac disease, or inflammatory or malabsorptive condition

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Frequency of bowel motion, assessed by bowel habit diary[Bowel movements monitored on a daily basis throughout the 3 weeks (21days) of kiwifruit extract supplementation; assessed at baseline and immediately after the completion of the intervention (21 days from start of kiwifruit extract supplementation)<br>]

Secondary Outcome Measures

Name	Time	Method
Microbiota community, extract DNA for 16S pyrosequencing of microbiome[5g faecal sub-sample collected at baseline (day0) and collected at the end of intervention (day21).];QSRS (gastrointestinal symptom rating scale) [Assessment form collected at day0 and day21 of intervention period. ];Ease of passing of stools, consistency and volume of stools; assessed by bowel habit diary entry comparison to Bristol Stool Form Chart.[Bowel movements monitored on a daily basis throughout the 3 weeks (21days) of kiwifruit extract supplementation; assessed at baseline and immediately after the completion of the intervention (21 days from start of kiwifruit extract supplementation). <br>]