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Clinical Trials/NCT03332199
NCT03332199
Completed
N/A

A Psycho-educational Intervention for Symptom Cluster Management Among Cancer Patients Undergoing Chemotherapy in Vietnam

Hanoi Medical University1 site in 1 country102 target enrollmentSeptember 1, 2016
ConditionsCancerOncology

Overview

Phase
N/A
Intervention
Not specified
Conditions
Cancer
Sponsor
Hanoi Medical University
Enrollment
102
Locations
1
Primary Endpoint
Symptom cluster
Status
Completed
Last Updated
8 years ago

Overview

Brief Summary

The purpose of this study is to develop, implement and undertake a preliminary evaluation of a psychoeducational intervention for managing a cancer-related symptom cluster including pain, fatigue and sleep disturbance experienced by Vietnamese cancer patients.

Registry
clinicaltrials.gov
Start Date
September 1, 2016
End Date
October 20, 2017
Last Updated
8 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Hanoi Medical University
Responsible Party
Principal Investigator
Principal Investigator

Ly Nguyen

Principal Investigator

Hanoi Medical University

Eligibility Criteria

Inclusion Criteria

  • Are diagnosed with any type of cancer
  • Are over 18 years of age
  • Have finished the second chemotherapy cycle
  • Expected prognosis of at least 12 months
  • Karnofsky level of ≥ 60/
  • Report three symptoms: fatigue, pain and sleep disturbance at severity level of equal or above 3 during the past 7 days.
  • Ability to communicate in Vietnamese

Exclusion Criteria

  • Inability to complete questionnaires or participate in the intervention due to literacy level or communication impairment.
  • Have been diagnosed with major psychiatric morbidity such as suicidal tendencies or schizophrenia.
  • Involved in other clinical trials

Outcomes

Primary Outcomes

Symptom cluster

Time Frame: 4 weeks

The three-single item Numeric Analogue Scales (fatigue, pain and sleep disturbance) were used at baseline and 4 weeks of the intervention to assess the change of symptom severity at cluster levels. The scales consists of a number of symptoms rated on the 11-point scales, with 0 referring to "not present" and 10 referring to "as bad as you can imagine". The symptom cluster severity was evaluated by averaging symptom summary scores, with a summary higher score indicating greater symptom cluster severity.

Fatigue

Time Frame: 4 weeks

The Brief Fatigue Inventory (BFI) was used to assess the change of fatigue from baseline to 4 weeks of the intervention. The BFI consists of nine items assessing severity of fatigue in the past 24 hours (4 items) and its impacts on patients' different aspects of life, such as daily activity, emotional well-being, walking ability, work, and social interactions (5 items) on a 11-point scale. A summary higher score indicating greater fatigue severity and interference.

Pain

Time Frame: 4 weeks

The Brief Pain Inventory was used to assess the change of pain from baseline to 4 weeks of the intervention. The Brief Pain Inventory - Short Form (BPI) encompasses a 4-item pain severity subscale and a 7-item pain interference with daily activities subscale. Each item was rated on 11-point numerical rating scales. A summary higher score indicating greater pain severity and interference.

Sleep disturbance

Time Frame: 4 weeks

The Pittsburgh Sleep Quality Index (PSQI) was used to assess patients' sleep quality and pattern at baseline and 4 weeks of the intervention. The scale consists of 19 self-reported items categorised in 7 domains, including sleep quality, duration, sleep effectiveness, sleep disturbances, sleep medication, and daytime dysfunction over the last month. Possible scores range from 0 to 21 with a higher score indicating greater sleep disturbance

Secondary Outcomes

  • Performance status(4 weeks)
  • Depression and Anxiety(4 weeks)
  • Health-related quality of life(4 weeks)

Study Sites (1)

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