A Prospective Multicenter Registry on Coronary Function Tests, Organized by the Belgian Working Group on Coronary Microcirculation/Belgian Microcirculation Registry.
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Coronary Microvascular Dysfunction
- Sponsor
- University Hospital, Antwerp
- Enrollment
- 650
- Locations
- 13
- Primary Endpoint
- Frequency of coronary microvascular dysfunction and/or coronary artery vasospasm
- Status
- Recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
The goal of this prospective, multicenter registy is to describe the 'real-world' use of coronary function tests, which may consist of bolus thermodilution measurements of coronary microvascular function and/or invasive vasoreactivity tests with acetylcholine, in the current Belgian routine practice. The main questions it aims to answer are:
- how frequent are coronary function tests performed
- what is the indication for coronary function tests
- what is the frequency of coronary microvascular dysfunction
- what is the frequency of coronary artery vasospasm
From each participant, data will be collected from their medical files concerning cardiovascular risk factors, relevant past medical history, non-invasive tests, procedural data, and follow-up data from routine in-patient visits. Their are no specific study visits. Optionally, patients will be asked to fill in questionnaires about anginal symptoms and quality of life.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Patient scheduled for coronary function test, comprising of intracoronary bolus thermodilution measurements of microvascular function, and/or intracoronary vasoreactivity tests with acetylcholine.
- •Subject understands the study requirements and provides written informed consent.
Exclusion Criteria
- •Subject is participating in another investigational clinical trial that may cause non-compliance with the protocol or confound data interpretation.
- •Subject intends to participate in another investigational clinical trial that may cause non-compliance with the protocol or confound data interpretation.
- •Documented or suspected pregnancy.
- •Inability to provide written informed consent.
Outcomes
Primary Outcomes
Frequency of coronary microvascular dysfunction and/or coronary artery vasospasm
Time Frame: 5 years
To measure the frequency of coronary microvascular dysfunciton coronary artery and vasomotor disorders among patients undergoing coronary function tests.
Secondary Outcomes
- Describe predictors for coronary microvascular dysfunction and/or coronary artery vasospasm(5 years)
- Describe 1- year and 3-year MACE among the different endotypes of coronary microvascular dysfunction with/whithout coronary artery spasm.(5 years)