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Clinical Trials/NCT04995263
NCT04995263
Recruiting
Not Applicable

A Multicomponent Intervention for Prevention and Treatment of Sleep Disturbances in a Psychiatric Intensive Care Unit: A Before-After, Randomized, Controlled Trial

Pontificia Universidad Catolica de Chile1 site in 1 country120 target enrollmentJune 22, 2021
ConditionsDyssomnias

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Dyssomnias
Sponsor
Pontificia Universidad Catolica de Chile
Enrollment
120
Locations
1
Primary Endpoint
Change in Total Sleep Time
Status
Recruiting
Last Updated
3 years ago

Overview

Brief Summary

Hospitalized adult patients suffer from sleep deprivation, which has been associated with multiple negative consequences, both in short and in the long term. Many factors have been attributed to poor sleep quality, including excessive noise, inappropriate lighting, interactions with the healthcare team, administration of drugs, patients' symptoms, among others. There is scarce evidence reporting multicomponent interventions aimed at ensuring and improving sleep quality in hospitalized patients. The following before-after, randomized controlled trial will evaluate and determine the feasibility, acceptability and effectivity of a multicomponent intervention in improving sleep quality and reducing the consequences of poor sleep in a psychiatric intensive care unit (PICU). The intervention is comprised of changes in health personnel habits, improvements in the PICU environment, patient's psychoeducation and continuous sleep and activity monitoring through a validated wearable device.

Registry
clinicaltrials.gov
Start Date
June 22, 2021
End Date
August 1, 2023
Last Updated
3 years ago
Study Type
Interventional
Study Design
Sequential
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Constanza Caneo

Clinical Assistant Professor, C-L Psychiatrist, SUEÑA Director

Pontificia Universidad Catolica de Chile

Eligibility Criteria

Inclusion Criteria

  • Hospitalized in the last 72 hours.
  • Capacity to consent
  • Approval by treating physician

Exclusion Criteria

  • Active psychosis
  • Active eating disorder
  • Major cognitive disorder

Outcomes

Primary Outcomes

Change in Total Sleep Time

Time Frame: From enrollment, during the first 72 hours of hospitalization, for up to 14 days or discharge.

Measured in hours and minutes, using objective data obtained via Fitbit Charge 4 devices, and subjective data obtained directly from the patient using the Sleep Diary, a consensus tool for the self report of different standardized sleep variables.

Secondary Outcomes

  • Change in Mean Number and Total Duration of Nocturnal Awakenings(From enrollment, during the first 72 hours of hospitalization, for up to 14 days or discharge.)
  • Level of Anxiety(From enrollment, during the first 72 hours of hospitalization, for up to 14 days or discharge. To be measured from the second branch onward, after the environmental interventions implementation.)
  • Change in Mean Number and Total Duration of Naps During the Day(From enrollment, during the first 72 hours of hospitalization, for up to 14 days or discharge.)
  • Change in Sleep Efficiency(From enrollment, during the first 72 hours of hospitalization, for up to 14 days or discharge.)
  • Change in Mean Heart Rate(From enrollment, during the first 72 hours of hospitalization, for up to 14 days or discharge.)
  • Change in Mean Number of Steps(From enrollment, during the first 72 hours of hospitalization, for up to 14 days or discharge.)
  • Change in Sleep Onset Latency Mean Duration(From enrollment, during the first 72 hours of hospitalization, for up to 14 days or discharge.)
  • Change in Wake After Sleep Onset Mean Duration(From enrollment, during the first 72 hours of hospitalization, for up to 14 days or discharge.)
  • Change in Average Time of Falling Sleep and Awakening(From enrollment, during the first 72 hours of hospitalization, for up to 14 days or discharge.)
  • Change in Sleep Architecture(From enrollment, during the first 72 hours of hospitalization, for up to 14 days or discharge.)
  • Change in Mean Level of Sound(From enrollment, during the first 72 hours of hospitalization, for up to 14 days or discharge.)
  • Change in Mean Level of Light(From enrollment, during the first 72 hours of hospitalization, for up to 14 days or discharge.)
  • Changes in Daytime Sleepiness(From enrollment, during the first 72 hours of hospitalization, for up to 14 days or discharge.)
  • Changes in Subjective Perception of Sleep-Disturbing Factors(From enrollment, during the first 72 hours of hospitalization, for up to 14 days or discharge.)
  • Level of Pain(From enrollment, during the first 72 hours of hospitalization, for up to 14 days or discharge. To be measured from the second branch onward, after the environmental interventions implementation.)
  • Change in 30-day Readmission Rate(30 days after the participant's discharge.)
  • Change in Participant Satisfaction Regarding Sleep During Hospitalization(7 days after the participant's discharge.)
  • Health Personnel Satisfaction and Agreeability Regarding the Intervention(Every 3 months through study completion, an average of 1.5 years)
  • Change in REM Onset Latency Mean Duration(From enrollment, during the first 72 hours of hospitalization, for up to 14 days or discharge.)
  • Changes in Sleep Quality Perception(From enrollment, during the first 72 hours of hospitalization, for up to 14 days or discharge.)
  • Changes in Pharmacological Indications and Need of SOS Medication(From enrollment, during the first 72 hours of hospitalization, for up to 14 days or discharge.)
  • Changes in Systolic and Diastolic Blood Pressure(From enrollment, during the first 72 hours of hospitalization, for up to 14 days or discharge.)
  • Change in Mean Length of Stay(From day 1 of hospitalization until discharge)
  • Participant Satisfaction Regarding the Intervention(7 days after the participant's discharge.)

Study Sites (1)

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