Breast activity and healthy eating after diagnosis - 2 During chemotherapy for early breast cancer

niversity Hospital of South Manchester (UK)0 个研究点目标入组 172 人开始时间: 2012年11月19日最近更新: 2023年3月13日

适应症

试验速览

2021 Results article in https://pubmed.ncbi.nlm.nih.gov/34912072/ (added 17/12/2021)

•1. Scheduled to have standard adjuvant or neoadjuvant chemotherapy
•2. Breast cancer stage I to III
•3. Any age >18 years: weight affects prognosis amongst preand
•post menopausal women
•4. BMI>19 Kg / m2 (Using IER and exercise we aim to avoid weight gain in all patients; this may lead to some weight
•loss in normal weight individuals).
•5. Ability to understand written instructions and have completed baseline 7 day diet and exercise diaries.
•6. Resident within Greater Manchester or Cheshire area only in order to maximise uptake and retention to interventions and study.
•7. Written informed consent

•1. Metastatic disease
•2. Previouly had chemotherapy for breast or any cancer within the last 2 years.
•3. Physical/or psychiatric conditions which may impair compliance to the diet or physical activity interventions assessed from medical history by recruitment nurse/ clinician i.e. Serious digestive and/or absorptive problems, including inflammatory bowel disease.
•Cardiovascular, respiratory (determined from recent preoperative
•ECG, chest X?ray, and verified from baseline fitness assessment by the trial exercise specialist (DM)
•Musculoskeletal disease or joint problems.
•Psychiatric disorders or conditions, e.g. untreated major depression, psychosis, substance abuse, severe personality disorder.
•4. Medications affecting weight e.g. metformin or continuous daily steroids (23 days with chemotherapy allowed)
•5. Insulin requiring diabetes, as diet and physical activity changes would require close coordination with the diabetiologist. Non-insulin
•requiring diabetics are eligible for the study.
•6. Already commenced chemotherapy.
•7. Scheduled to have weekly paclitaxel

发起方

niversity Hospital of South Manchester (UK)