Study to Measure Relaxation From Different Types of Focused Breathing Exercises

Phase 1

Terminated

• Conditions: Mind-body Practices; Meditation; Breathing; Yoga
• Interventions: Behavioral: Focused Breathing

• Registration Number: NCT02226744
• Lead Sponsor: Vanderbilt University Medical Center

Brief Summary

Mind-body practices, such as yoga, ta'i chi, mindfulness and biofeedback, commonly use slow breathing techniques to induce physiological and mental relaxation. Medical research suggests that slow breathing techniques induce physiological relaxation. This 6 week study will compare the effects of different types of breathing. The hypothesis is that different breathing techniques produce different physiological and mental changes.

Detailed Description

Not available

Study Timeline

• Study Start: 2014-08
• Study First Submitted: 2014-08-20
• Study First Submitted QC: 2014-08-25
• Study First Posted: 2014-08-27
• Primary Completion: 2015-12
• Study Completion: 2015-12
• Status Verified: 2016-12
• Last Update Submitted: 2016-12-30
• Last Update Posted: 2017-01-02

Recruitment & Eligibility

• Status: TERMINATED
• Sex: All
• Target Recruitment: 24

Inclusion Criteria

• Age 30 to 50 years
• English speaking

Exclusion Criteria

• Hypertension
• Heart disease: history of coronary artery disease, myocardial infarction, significant valvular disease, or congestive heart failure
• Diabetes
• Renal Disease
• Anxiety Disorder
• Depression
• Other psychiatric conditions including schizophrenia or bipolar disorder
• Attention-deficit-disorder or Attention-deficit-hyperactivity disorder
• Musculoskeletal condition limiting capacity to perform yoga such as chronic lower back pain, chronic neck pain
• Asthma
• Chronic Obstructive Lung Disease
• Obstructive Sleep Apnea
• Smoker
• Currently taking blood pressure medications, oral diabetic medication or insulin
• Current participation in a mind-body practice/program
• Current cancer other than non-melanoma skin cancer
• Regular swimmer
• Plays wind or brass musical instruments

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Focused breathing	Focused Breathing	Focused deep breathing techniques used to produce specific physiological and psychological states
Focused breathing 2	Focused Breathing	Focused deep breathing techniques used to produce specific physiological and psychological states

Primary Outcome Measures

Name	Time	Method
Magnitude of changes in heart rate response to upright position	10 minutes at baseline, 2 weeks and 6 weeks

Secondary Outcome Measures

Name	Time	Method
Magnitude of changes in heart rate variability measured as ratio of low frequency to high frequency ratio components (Hz)	Baseline, 2 weeks, and 6 weeks
Magnitude of changes in catecholamines in response to upright position	10 minutes at baseline, 2 weeks, and 6 weeks

Trial Locations

Locations (1)

Vanderbilt University Medical Center; 🇺🇸 Nashville, Tennessee, United States