Evaluation of a Feasible Frailty Assessment Tool for Preoperative Risk Evaluation of Older Patients
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 584
- 试验地点
- 2
- 主要终点
- Complications in the first 30 days after surgery
研究概览
简要总结
Frailty is a significant risk factor for postoperative complications and functional decline. Preoperative assessment of frailty is therefore recommended in all older adults. However, despite the availability of many frailty tools, few have been tested in the preoperative setting and there is little comparison of their predictive value in identifying patients at risk. The aim of this study is to investigate which of the following instruments for determining frailty has the highest predictive power with regard to the occurrence of postoperative complications: Risk Analysis Index, Clinical Frailty Scale, the Groningen Frailty Indicator, the Edmonton Frail Scale and the LUCAS-FI. The aim of this research project is to identify a suitable frailty instrument for preoperative risk stratification of older patients during the premedication visit.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 70 Years 至 —（Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •70 years and older
- •scheduled surgery
- •estimated time of surgery 120 Minutes or more
排除标准
- •insufficient German language skills (for cognitive testing)
- •mental retardation
- •relevant psychiatric disorder (not allowing for cognitive testing)
结局指标
主要结局
Complications in the first 30 days after surgery
时间窗: 30 days
Measured by Clavien-Dindo classification
次要结局
- Discharge destination(up to 4 weeks after surgery)
- Cognitive state(3 and 6 months after surgery)
- Quality-of-Life (QoL)(3 and 6 months after surgery)
- Frailty progression measured by LUCAS-FI(3 and 6 months after surgery)
- Functional state (activities of daily living)(one, three and six months after surgery)
- Postoperative Quality of Recovery(postoperative day 2)
- Muscle loss during hospitalisation(From date of enrollment, up to 4 weeks after surgery)
- Postoperative delirium(postoperative day 1 to 5)
- Length of stay(from day of surgery, up to 4 weeks after surgery)
- Frailty progression measured by GFI (questionnaire)(3 and 6 months after surgery)
- Frailty progression by RAI measurement. The Risk Analysis Index (RAI) is evaluated by summing weighted risk factors and protective variables, with higher scores indicating greater patient vulnerability.(3 and 6 months after surgery)
- Frailty progression measured by EFS(3 and 6 months after surgery)