The PLAN Project: Pregnancy Lifestyle Activity and Nutrition: effectiveness of maternal lifestyle intervention commenced before 10 weeks gestation, in normal, overweight and obese mothers on maternal behaviours and infant's adiposity.

Phase 1

Completed

• Conditions: Obesity; Diet and Nutrition - Obesity

• Registration Number: ACTRN12617000725369
• Lead Sponsor: Telethon Kids Institute

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2017-05-18
• Last Update Posted: 15 July 2019

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 80

Inclusion Criteria

Pregnant women who are recruited at <10 weeks gestation and have a pre-pregnancy BMI of >20, or BMI >18 in high-risk ethnic groups.

Exclusion Criteria

Women with a current diagnosis of a serious pre-existing medical condition (e.g. type 1 or 2 diabetes, psychosis, eating disorder, thyroid condition or on medication for Polycystic Ovarian Syndrome)
Multiple births

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Gestational weight gain in kg between start of intervention and to end of 12 weeks intervention[Measured between start of intervention to end of 12 week intervention.];Neonatal and infant body fat percentage measured using the Cosmed PeaPod, a non-invasive assessment that uses air-displacement plethysmography. [Birth];Rate of gestational weight gain during pregnancy in kg/week.[At enrolment and 36 weeks gestation]

Secondary Outcome Measures

Name	Time	Method
DNA methylation assessed on DNA extracted from cord blood[Birth];Glucose tolerance as ascertained by routine oral glucose tolerance test at 28 weeks gestation[28 weeks gestation]