Near-Infrared Red Spectroscopy (NIRS) to Measure Cerebral Perfusion During and After Patent Ductus Arteriosus (PDA) Treatment in Very Low Birth Weight (VLBW) Infants
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Singapore General Hospital
- Enrollment
- 30
- Locations
- 1
- Primary Endpoint
- cerebral oximetry
Study Overview
Brief Summary
Aim of study:
To conduct an observational study to collect cerebral and renal perfusion data through NIRS before and after treatment of PDA by medication or by PDA ligation. The data post treatment would form the basis for normative baseline data in VLBW preterm newborn babies, particularly in the Asian population.
Study population/inclusion criteria:
VLBW newborn babies with hemodynamically significant PDA by echocardiography.
Exclusion criteria:
Major malformations Moribund patients
Detailed Description
Aim of study:
To conduct an observational study to collect cerebral and renal perfusion data through NIRS before and after treatment of PDA by medication or by PDA ligation. The data post treatment would form the basis for normative baseline data in VLBW preterm newborn babies, particularly in the Asian population.
Study population/inclusion criteria:
VLBW newborn babies with hemodynamically significant PDA by echocardiography.
Exclusion criteria:
Study Design
- Study Type
- Observational
- Observational Model
- Cohort
- Time Perspective
- Prospective
Eligibility Criteria
- Ages
- — to 6 Months (Child)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •VLBW infants with hemodynamically significant PDA by echocardiography
Exclusion Criteria
- •Major malformation
Outcomes
Primary Outcomes
cerebral oximetry
Time Frame: 2 years
Secondary Outcomes
- renal oximetry(2 years)