Efficacy of Two Different Doses of Labetalol Hydrochloride for Attenuation of Haemodynamic Response to Laryngoscopy and Endotracheal Intubation in Controlled Hypertensive Patients â?? Prospective Randomized Double Blind Comparative Study

SSG Hospital0 个研究点目标入组 0 人开始时间: 待定最近更新: 2021年11月24日

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•We include ASA grade II patients posted for planned surgery under general anasthesia requiring orotracheal intubation and having controlled hypertension.

•Patients who refuse to give consent.
•Pregnant and lactating women.
•Anticipated difficult airway and obesity(BMI >35).
•Patient having allergy to study drug.
•Patient with sick sinus syndrome (including sino-atrial block),second or third degree heart block and persistent bradycardia ( <45-50 bpm).
•Patients is having history of taking medication for any sort of illness like verapamil, diltiazem, digitalis glycosides, clonidine, monoamineoxidase inhibitors (except MOA-B inhibitors) and beta blocker.
•Patient with systemic diseases like cardiovascular, respiratory diseases like bronchial asthma and COPD, neurological, psychological, hepatic, untreated phaeochromocytoma,renal disease (diagnosed by clinical judgments and investigations) and on medication of above mentioned diseases.
•Time more than 20s or requiring more than two attempts for laryngoscopy and intubation.

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