Effect of Interval Inspiratory Muscle Training on Autonomic Dysfunction and Blood Pressure in Hypertensive Adults: A Randomized Controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 28
- 试验地点
- 2
- 主要终点
- Resting heart rate
研究概览
简要总结
This study finds the effectiveness of inspiratory muscle threshold loading training among adults with hypertension. A sample of hypertensive subjects was divided into two groups - inspiratory muscle training (IMT) - group (inspiratory muscle training was prescribed) and sham-group (no load was prescribed during IMT). Both groups had training sessions comprising seven cycles of two minutes bouts of breathing counter to an inspiratory load, each bout parted by one minute of unloaded recovery. Treatment session was performed for three times per week for a total of six weeks. Measurement of each of the variables (blood pressure, resting heart rate (RHR), heart rate variability (HRV)) was taken at baseline and after the six-week intervention.
详细描述
The present study aimed to examine the outcome of interval inspiratory muscle training at 70% load on blood pressure, resting heart rate and autonomic dysfunction in the hypertensive adults.
Participants were divided into two groups: IMT and sham. In IMT group, the threshold loading inspiratory muscle trainer from POWERbreathe was used with 70% IMT threshold. In Sham group, IMT was unloaded.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
盲法说明
Outcome assessor was kept blind to the allocation of participants.
入排标准
- 年龄范围
- 30 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •stage 1 hypertension
- •essential hypertension
- •mild hypertension
排除标准
- •Subjects participating in exercise training for more than the last six months
- •severe musculoskeletal limitations
- •severe neurological limitations
- •cognitive impairments
- •uncontrolled diabetes
- •uncontrolled hypertension
- •a history of myocardial infarction (MI)
- •a history of stroke in the last six months
- •unstable angina
- •chronic heart failure
- •pulmonary disease of any etiology
结局指标
主要结局
Resting heart rate
时间窗: 6 weeks
Resting heart rate was measured at baseline and after completion of intervention.
Blood pressure
时间窗: 6 weeks
Systolic and diastolic blood pressures were measured at baseline and after completion of intervention.
Autonomic functions
时间窗: 6 weeks
Autonomic functions were assessed by measuring the heart rate variability parameters at baseline and after completion of intervention.
次要结局
未报告次要终点
研究者
Masood Khan
Principal Investigator
King Saud University