Skip to main content
Clinical Trials/NCT04731142
NCT04731142
Completed
Not Applicable

Type 2 Diabetes Exemplar (T2DEx): A Remote Care Service for North West London

Imperial College London7 sites in 1 country235 target enrollmentJune 1, 2021

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Type 2 Diabetes Mellitus
Sponsor
Imperial College London
Enrollment
235
Locations
7
Primary Endpoint
Number of Deaths
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

The aim of T2DEx is to assess the feasibility, usability, acceptability, cost-effectiveness and safety of a digital support service for people in North West London at high risk of developing complications from Type 2 Diabetes Mellitus (T2DM).

Detailed Description

The Type 2 Diabetes Exemplar Programme has been designed as a collaborative effort through partners from the Discover-NOW Health Data Research Hub in North West London (NWL). The remote care service is being used in primary care to demonstrate how data and technology can improve health outcomes for people living with T2DM. The service has been designed via a cross-industry collaboration between North West London Clinical Commissioning Groups (NWL CCGs), AstraZeneca, Imperial College Health Partners and Huma. The service will be offered for patients at high risk of developing complications from T2DM (such as heart attack and stroke) and will combine video group consultations, remote monitoring via a smartphone app, and educational content such as lifestyle and diet advice. This service seeks to strengthen population health management by providing better-tailored services and proactive interventions, particularly among population groups more at risk of the adverse impacts of COVID-19. Mortality risk from COVID-19 is approximately 25% higher in patients with T2DM and shielding has resulted in reduced primary care appointments for patients with T2DM. This has created an immediate need for primary care to adapt to provide care remotely to people with T2DM. Digital-first remote pathways could make care more accessible while finding time and cost efficiencies. By combining video group consultations and remote monitoring, we can inform the patient-clinician conversation making remote care in group settings safer, efficient and more personalised.

Registry
clinicaltrials.gov
Start Date
June 1, 2021
End Date
October 31, 2022
Last Updated
2 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Patients over the age of 18 with the capacity to give consent
  • Patients with 'high risk' OR 'very high risk' T2DM as defined by:
  • Very high risk - T2DM with existing ASCVD OR T2DM without ASCVD but with any 3 of the following:
  • HbA1c \>58
  • SBP \>140
  • Non-HDL \>3.35 or LDL-C \>2.5
  • Nephropathy (eGFR \<45, or Urine ACR \>3)
  • Retinopathy
  • Neuropathy (including moderate/high risk feet, previous foot ulceration and erectile dysfunction)
  • Currently smoking

Exclusion Criteria

  • Participants too ill to participate in the study (i.e., presence of a life-threatening condition, expected survival less than 3 months, clinically unstable)
  • Participants who have previously participated in efforts that have informed the design of this research.
  • Participant without access to a smartphone.
  • Non-English language (the remote monitoring technology currently does not support additional languages).
  • Visual disability (the remote monitoring technology currently does not natively support visual assistance).
  • Active severe mental illness (SMI).
  • Alcohol / drug abuse.
  • Severe frailty (identified via the Electronic Frailty Index - eFI).
  • Housebound / living in nursing home.
  • Currently on the REWIND Programme (a NWL total diet replacement programme for patients with type-2 diabetes).

Outcomes

Primary Outcomes

Number of Deaths

Time Frame: 12 weeks

Number of Participants With Emergency Department Admissions

Time Frame: 12 weeks

Blood Pressure Measurements Recorded

Time Frame: 12 weeks

Number of participants entering at least one blood pressure measurement

Number of Diabetes Distress Scale Scores Recorded

Time Frame: 12 weeks

Number of participants entering at least one DDS measurement

Video Group Consultation Sessions Attended

Time Frame: 12 weeks

the number of participants attending at least one VGC

Number of Weight Measurements Recorded

Time Frame: 12 weeks

Number of participants entering at least one weight measurement

Blood Glucose Measurements Recorded

Time Frame: 12 weeks

Number of participants entering at least one measurement

% Participants Downloading Huma App

Time Frame: 12 weeks

Number of Participants With Hospital Admissions

Time Frame: 12 weeks

Secondary Outcomes

  • Change in HbA1c(6 months)
  • Change in Systolic Blood Pressure(6 months)
  • Change in Total Cholesterol(6 months)
  • Change in Weight(6 months)

Study Sites (7)

Loading locations...

Similar Trials